Related Episodes for How Exercise and Sleep Support Immune Function With Age

In this clip, Dr. Patrick explains how intense exercise beneficially alters tryptophan and kynurenine metabolism in a way that may benefit depression.

“Dr. McGlory sheds light on the relationship between aerobic conditioning and muscle hypertrophy, addressing the notion that aerobic exercise might hinder muscle growth gained through resistance training.”

“Metformin, a drug commonly used to treat type 2 diabetes, has garnered interest as a longevity compound because it was shown to extend lifespan in some animal models. These effects are variable and seem to depend on the age and gender of the animals, as well as the dose provided.”

“In this clip, Drs. Levine and Patrick discuss definitions of aging used in science and why biological aging matters to scientists. Dr. Levine shares the hallmarks of aging that help researchers determine someone's biological age, what drives accelerated aging, and what epigenetic modifications such as CpG methylation say about the aging process.”

“The stability of DNA methylation patterns - in terms of sample reliability - makes the use of epigenetic clock data an attractive tool in the hands of researchers investigating aging around the world.”

“Removing former drinkers from the non-drinker category reveals a different story: One study observed that the lowest risk for cardiovascular disease (i.e., ischemic heart disease) was right below one standard U.S. drink per week — men and women at this level of consumption had an ~18% lower risk compared to nondrinkers.”

“Dr. Huberman’s practical range is deliberately cautious: not drinking avoids the exposure, and lower weekly intake creates less burden than a drink every night or heavier episodes.”

“Dr. Rhonda Patrick spent many months researching and learning about the myriad factors that would influence her child's development, and she has continued to do so as her son has grown – and as new research has become available.”

“Rebuilding muscle relies on proper nutrition and exercise, but aging reduces the body's response to both. Extended periods of inactivity, such as post-surgery or during illness, can rapidly deplete muscle mass, especially in older people, potentially pushing them into a "catabolic crisis."”

“Scientists are exploring a wide range of cutting-edge therapies aimed at understanding and manipulating the complex processes underlying these hallmarks, including epigenetic aging clocks and pluripotent stem cells.”