Related Episodes for Immune stimulation may treat depression via cytokines that boost neurotrophic factors | Charles Raison

“Some researchers have hypothesized that since antihypertensive drugs like ACE inhibitors and angiotensin II receptor blockers, or ARBs, increase ACE2, they might alter the risk of severe COVID-19 disease.”

“Approximately 25 percent of people in the United States – roughly 75 million people – carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”

“Dr. Attia and Dr. Patrick agree that avoiding low vitamin D status is the clearest goal. Large prospective analyses consistently find higher risk at low 25-hydroxyvitamin D concentrations, while the evidence becomes less certain once people reach sufficiency.”

“- Axel Montagne, Ph.D. While we await potential breakthroughs in targeting elements of the neurovascular unit in the blood-brain barrier directly with stem cell therapeutics, gene therapies, and other cutting-edge techniques, there are things we can do now to better support vascular health and thereby help maintain the integrity of the blood-brain barrier.”

“An enriched marine-oil study produced time- and dose-dependent increases in specialized pro-resolving mediators and altered blood-cell responses over 24 hours; it tested biomarkers, not disease prevention. Exercise, sauna, and cruciferous vegetables act through different pathways.”

“Unique qualities of the marine omega-3 fatty acids EPA and DHA There are several omega-3 fatty acids, but the ones that have the greatest relevance for human health are the two identified in the Inuit's blood – EPA and DHA – as well as alpha-linolenic acid (ALA), which is found in a wide variety of seeds, nuts, and their oils.”

“Scientists are using artificial intelligence to analyze databases of facial images from people of different ages matched with metabolites in order to develop biomarkers. Other researchers are studying blood markers from people of different ages to create an aging curve.”

“As a starting point, Dr. Attia suggests people consume just enough protein to maintain and grow muscle mass. The oral glucose tolerance test, which monitors glucose and insulin levels, can be used to determine carbohydrate limits.”

“Biomarkers can be used to track how the body is responding to a dietary intervention or exercise program. To assess his body's response to the ketogenic diet, Tim routinely measures his blood ketone level - observing that his level of blood ketones closely reflects his state of mental clarity.”

“In a separate analysis of seven intervention trials involving people with type 2 diabetes, HbA1c fell by about 0.71 percentage points, total cholesterol by 23 mg/dL, and LDL cholesterol by 22 mg/dL.”