Related Episodes for Lack of deep sleep linked with amyloid-beta build up in Alzheimer's disease | Matthew Walker

“Few topics come up in their discussion where Dr. Fahey doesn't have an anecdote about a study he was involved in, or, in some cases, "tribal knowledge" that may not even be published but is nonetheless interesting and an important part of the story that is unique to his particular vantage point.”

Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX.

“Study. 01:43:00 - High animal protein intake was only positively associated with cardiovascular mortality among individuals with at least one unhealthy lifestyle risk factor, such as obesity or sedentary lifestyle. Study.”

“1 02:37:05 - Mothers that chew xylitol gum starting mid-pregnancy and continuing until 6-12 months after birth lowered the oral streptococcus mutan bacteria, which is an anaerobic bacteria that plays a significant role in tooth decay, in their toddlers/children.”

“00:34:40 - Repeated traumatic brain injury has cumulative neuroinflammatory effects in the brain over years, including amyloid-beta plaque and tau tangle formation. Study. 00:44:00 - A variant of the APOE gene increases risk of developing Alzheimer’s disease as much as 15-fold.”

“Finally, choline is also a precursor for phosphatidylcholine, the major component of all cell membranes, which affects the structure, permeability and function of cells and is particularly important in neurons since it plays a role in general neurotransmission.”

“Dr. Patrick recommends bounded quality checks such as GMP manufacturing and independent testing; she notes that some tested products were below their stated heavy-metal limits, not that lion’s mane products are uniformly contaminated.”

“The mast cells release pro­inflammatory cytokines and proteases that damage the gut, leading to intestinal permeability, a condition otherwise known as “leaky gut.” This leakiness allows bacteria and bacterial antigens to cross the gut’s inner layer, the epithelium, and activate even more immune cells, leading to more inflammation – a key driver in the aging process.”

“Another randomized study found better long-term picture-location memory when exercise occurred four hours after learning, showing that timing can shape the result. Dr. Patrick also discusses serotonin and hippocampal neurogenesis as a possible biological link.”

“While Dr. Rhonda Patrick’s first video focused primarily on the micronutrients found in the various fruits and vegetables she put in her smoothie, this one, in addition to offering some modest changes on the recipe, instead focuses on the beneficial “hormetic” compounds that are NOT micronutrients.”