Related Episodes for Metformin and reductions in cancer death | Rhonda Patrick

“Imaging studies also associate higher visceral fat with increased cancer incidence in some populations, while large cohort analyses link greater waist circumference with higher all-cause mortality.”

“In more than 25,000 adults who reported no structured exercise, about three short vigorous bouts per day were associated with 38 to 40 percent lower all-cause and cancer mortality and 48 to 49 percent lower cardiovascular mortality compared with no vigorous bouts.”

In this clip, Dr. Patrick explains how intense exercise beneficially alters tryptophan and kynurenine metabolism in a way that may benefit depression.

“Mitochondria are best known for their energy-producing roles, but they also help regulate cellular metabolism, signaling, and apoptosis (programmed cell death). As a result, mitochondrial health is intrinsically linked to overall health.”

“Mitochondrial health and overall health are intrinsically linked. Identifying ways to boost mitochondrial biogenesis – the formation of new mitochondria – ensures that cells maintain an adequate number of mitochondria to meet their energy needs.”

“In this Aliquot, I walk through how that plays out in humans, where the strongest evidence shows up, and where it doesn't, with NAD researcher Dr. Charles Brenner—and why I'm taking it now after being skeptical.”

“A more useful approach is to focus on what you can do to reduce its effects. In this Aliquot, Dr. Kelly Starrett explains why standing more is not enough, how to build movement into your workday, and why it matters for long-term mobility.”

“Time-restricted eating, which involves taking in food within a small window of time during the day and fasting for the remainder, can improve certain biomarkers of health – even without weight loss – to improve overall health. In Part I of this two-part segment, Drs.”

“Coordination of meal timing with the circadian rhythm can reduce markers of inflammation and affect aspects of metabolic health, including glucose regulation and insulin sensitivity. Animal studies suggest that overnight fasting induces autophagy.”

“The timing of eating and exercise, especially in elite athletes, hasn't been studied and may, in fact, require self-experimentation by the athletes to identify the perfect interval of fasting to support their optimal performance.”