Related Episodes for How does the gut microbiome respond to extreme dietary change? | Dr. Eran Elinav

“In this clip, Drs. Levine and Patrick discuss genetic and environmental factors that can accelerate or slow epigenetic aging. Dr. Levine also discusses the aging clock she created and how it can be used, along with other biomarkers, to determine an individual's rate of aging.”

“Dr. Patrick explains some of the early evidence that suggests the value prolonged fasting (48+ hours) may have from the standpoint of tissue rejuvenation and healthspan maintenance, as well as relevance for other more specific conditions.”

“A large meta-analysis found that protein supplementation improved resistance-training gains in muscle size and strength, with little additional lean-mass benefit above an estimated total intake of about 1.6 grams per kilogram per day for most participants.”

“In this clip from his FoundMyFitness interview with Dr. Rhonda Patrick, Dr. Derya Unutmaz presents an optimistic vision in which AI, biotechnology, and rapidly improving treatments help more people remain healthy long enough to benefit from the next generation of therapies.”

“A dose-response meta-analysis of 30 prospective studies, including more than 1.18 million participants, associated each additional daily cup with about a 6 percent lower incidence of type 2 diabetes, with similar patterns for caffeinated and decaf coffee.”

“Time-restricted eating can help some people reduce eating opportunities, although a 12-month trial found no additional weight or body-fat benefit when an eight-hour eating window was added to calorie restriction. Sleep also affects appetite and fat distribution.”

“Visceral fat can respond to changes in energy balance and physical activity. A meta-analysis of 40 randomized trials and 2,190 adults with overweight or obesity found that both exercise and calorie restriction reduced CT- or MRI-measured visceral fat.”

“During about eight years of follow-up, the models associated one vigorous minute with roughly 4.1 moderate minutes for all-cause mortality, 7.8 minutes for cardiovascular mortality, and 9.4 minutes for type 2 diabetes risk.”

“In a randomized crossover study of 18 young men with overweight or obesity, ten 3-minute walking or squat breaks spaced across 8.5 hours lowered post-meal glucose exposure more than uninterrupted sitting or one continuous 30-minute walk.”

“In a small study of 10 men, twice-weekly sauna sessions for three months altered sperm production and function, with recovery documented during follow-up after sauna use stopped. Sperm outcomes and circulating testosterone are distinct measures of reproductive function.”