Related Episodes for Mitophagy: a signal for mitochondrial biogenesis, metabolic adaptation, and cellular differentiation

“A four-week pilot study in people with type 2 diabetes reported improved insulin-stimulated glucose disposal after oral alpha-lipoic acid, while a three-week randomized trial found that intravenous 600 milligrams per day reduced diabetic neuropathy symptoms.”

“Early biomarkers of vascular dysfunction, such as soluble platelet-derived growth factor receptor-beta (sPDGFR-β), can help identify individuals at risk for developing Alzheimer's disease. These biomarkers are being validated on high-throughput platforms for large-scale testing.”

“Consensus evidence supports ApoB as a causal risk factor, but Dr. Attia’s proposed 10–30 mg/dL physiological range and treatment targets are attributed opinions, not universal guideline targets. Diet can change ApoB through several pathways.”

“Approximately 25 percent of people living in the United States carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”

“The ketogenic diet is contraindicated in people with pancreatitis, fat metabolism disorders, and other rare metabolic conditions. Some people carry a version of the apolipoprotein E gene called APOE4 – a risk factor for late-onset Alzheimer's disease.”

“Dr. Krauss explains how some people might be inappropriately prescribed statins while other people should be taking statins. In addition, his current research is investigating whether statins can increase the risk of diabetes, especially for women.”

“Premenopausal females have much lower rates of cardiovascular disease than similarly aged males because of the protective effects of estrogen, but after menopause, there's not much of a difference, and cardiometabolic risk factors actually worsen in females during the menopause transition, indicating this may be a crucial time for exercise intervention to protect the cardiovascular system.”

“In this clip, Dr. Dominic D'Agostino explains the interrelationship between ketones and lactate as sources of energy for the brain and the role ketones may have in reducing oxidative stress through greater energetic efficiency.”

“I am simply choosing not to blend them into my blueberry smoothie when the goal is to maximize polyphenol exposure.".(https://www.foundmyfitness.com/episodes/blueberries)'] A 2023 banana-smoothie study caught Rhonda's attention because the effect was unusually large and the mechanism made biological sense.”

“Dr. Patrick begins with a prospective Finnish cohort in which men reporting four to seven sauna sessions per week had lower dementia and Alzheimer's disease incidence than men reporting one session. The study is observational, male-only, and cannot prove that sauna caused the lower risk.”