Related Episodes for MTHFR gene and supplementation with 5-L-methylfolate | Tim Ferriss

“Melatonin appears in the comparison as a personal, goal-specific choice rather than a universal nightly supplement. Dr. Patrick also discusses glycine, collagen, myo-inositol, and other non-overlapping items with different levels of evidence.”

“In a 12-week randomized trial of 291 adults living in a region of China with substantial air pollution, a broccoli-sprout beverage increased urinary excretion of a benzene metabolite by 61 percent and an acrolein metabolite by 23 percent.”

“A pooled analysis of 1,422 participants from 14 intervention trials found that supplemented participants took an average of 1,983 milligrams of EPA plus DHA per day for about 13.6 weeks, while their mean Omega-3 Index rose from 4.9% to 8.1%.”

“In this Institute for Functional Medicine excerpt, Dr. Rhonda Patrick frames omega-3 intake as beneficial and argues that low contaminant exposure should be weighed against the nutritional value of EPA and DHA. Her benefit-risk view does not mean omega-3 negates mercury or PCB toxicity.”

“In this FoundMyFitness Premium Q&A preview, Dr. Rhonda Patrick reviews common contributors to fragmented sleep, including insomnia, sleep apnea, nocturia, psychological stress, irregular schedules, caffeine, alcohol, light, noise, temperature, and late eating.”

“Family-controlled research provides another view. A Swedish cohort of 2.48 million children found small associations in conventional models, but the estimates moved to the null when siblings with different prenatal exposure were compared.”

“Dr. van Loon sees useful research questions in skin, joints, and recovery after orthopedic surgery, but he keeps those possibilities separate from established muscle-building effects.”

“Fasting can deplete the body's stores of electrolytes, especially during prolonged fasts or during periods of exercise when electrolytes can be lost during sweat. Because electrolytes are non-calories, replenishment does not appear to alter circadian rhythms.”

“While it’s likely that there may be more going on with depression than just inflammation by itself, it could be an incredibly useful lens through which to look at promising avenues to potentially treat or prevent it, since controlling systemic inflammation shows promise as being both important for longevity and health in general.”

“In this clip, Dr. Valter Longo describes how a fasting-mimicking diet can reduce markers of inflammation, such as C-reactive protein and Interleukin-6, possibly by killing damaged cells and regenerating others and resetting the system back to a more youthful state.”