Inflammation as a biomarker of successful aging — evidence in semi-supercentenarians

Parent Episode: Valter Longo, Ph.D. on the Fasting-Mimicking Diet & Fasting for Longevity, Cancer & Multiple Sclerosis

Inflammation is a critical element of the immune response and occurs when the body is exposed to harmful stimuli, such as pathogens, damaged cells, or irritants. Some scientific evidence indicates that centenarians, those who live to 100 years of age, have lower biomarkers of inflammation. Long-lived people eventually develop age-related diseases – just later in life. The onset of these inflammatory diseases may occur when genetic programs which have given them an advantage begin to falter. In this clip, Dr. Valter Longo describes how a fasting-mimicking diet can reduce markers of inflammation, such as C-reactive protein and Interleukin-6, possibly by killing damaged cells and regenerating others and resetting the system back to a more youthful state.

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