Ranked by shared topics, with one result from each original episode.
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“Metformin, a drug commonly used to treat type 2 diabetes, has garnered interest as a longevity compound because it was shown to extend lifespan in some animal models. These effects are variable and seem to depend on the age and gender of the animals, as well as the dose provided.”
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“The fact that poor sleep is linked with the aggregation of amyloid-beta plaques in the brain and Alzheimer's disease is not surprising. Although some strategies for improving the quality of sleep among people with Alzheimer's have been identified, this might be too late to turn the tide of cognitive decline.”
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“In this clip, Dr. Michael Snyder discusses how people age in distinct ways and at varying rates and how knowing our "ageotype" might offer targets for preventing age-related diseases.”
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“Young people usually bounce back from muscle loss quite quickly, but for older adults, the stakes are higher, as repeated inactivity can lead to irreversible muscle loss and diminished strength, critically impacting their daily activities.”
“Dr. Rhonda Patrick spent many months researching and learning about the myriad factors that would influence her child's development, and she has continued to do so as her son has grown – and as new research has become available.”
“Rebuilding muscle relies on proper nutrition and exercise, but aging reduces the body's response to both. Extended periods of inactivity, such as post-surgery or during illness, can rapidly deplete muscle mass, especially in older people, potentially pushing them into a "catabolic crisis."”
“A May 2025 Nature paper showed taurine uptake may fuel aggressive myeloid leukemias in laboratory and mouse models, illustrating how nutrients beneficial to healthy tissues may also feed certain cancers.”
“In this Aliquot, Drs. Peter Attia, Stuart Phillips, Morgan Levine, Brad Schoenfeld, Michael Snyder, Valter Longo, Martin Gibala, George Church, as well as Kevin and Darya Rose and myself, share our strategies for finding our fitness.”
“Martin Gibala, Bill Harris, and Peter Attia about three proven ways to promote health and longevity: boosting cardiorespiratory fitness, ensuring you're getting plenty of omega-3 fatty acids, and maintaining healthy blood glucose levels.”
“However, dietary strategies, pharmaceuticals, and some supplements may reduce ApoB levels. In this Aliquot – a follow-up to Aliquot #81 – Dr. Peter Attia and I talk about some of the nutritional, pharmaceutical, and supplemental approaches to reduce ApoB.”