Related Episodes for Are there sex differences in gaining mass and strength? | Dr. Chris McGlory

Hormesis is a compensatory defense response to a stressor that conditions the body against future stressors. Heat exposure – from sauna use, hot tubs, or eve...

“However, combining fasting with resistance training can stimulate muscle growth. In this Aliquot, Dr. Rhonda Patrick discusses time-restricted eating, fasting, and muscle preservation, highlighting key differences and offering recommendations for specific groups.”

“In this FoundMyFitness interview clip with Dr. Rhonda Patrick, Dr. Layne Norton places creatine monohydrate in his highest evidence tier because it supports repeated high-intensity performance, strength, and gains in lean mass.”

“Another study suggests that intermittent fasting combined with exercise training increased serum ketone levels, increased the number of mitochondria in muscle cells, and improved endurance. In this clip, Dr. Mark Mattson describes how fasting and exercise work together to promote brain health.”

“Timing provides a practical compromise. Dr. van Loon favors protecting the first several hours after resistance or endurance training, then placing cold exposure later in the day or on a recovery day when muscle adaptation is the priority.”

“Perhaps the most clear-cut examples of cryotherapy’s beneficial effects are observed in the brain, where levels of the hormone and neurotransmitter norepinephrine – responsible for vigilance, attention, focus, and positive mood – increase markedly when the body is exposed to extreme cold.”

“Creatine works by building tissue stores, so consistent daily intake matters more than taking it immediately before a specific workout. Dr. Patrick and Dr. Candow also discuss its value during aging, when preserving training quality and muscle becomes increasingly important for function and independence.”

“Contrary to the traditional view of lactate as a metabolic waste product, it is now recognized for its critical role in brain health. Elevated lactate levels after vigorous exercise are linked to improved executive function, hinting at its potential protective benefits against neurodegenerative diseases.”

“The physical activity guidelines and estimates on how much activity we need are heavily based on self-reported activity, which is useful but imperfect: people remember going for a run, but they forget the short, intense bursts in daily life like sprinting up stairs, chasing kids, and running to catch a bus.”

“Dr. Patrick describes increased shear as a possible way vigorous exercise can damage fragile circulating tumor cells; this is a proposed mechanism, not proof that a workout eliminates metastasis or treats an established tumor.”