Related Episodes for Are there sex differences in gaining mass and strength? | Dr. Chris McGlory

“In this clip from his FoundMyFitness interview with Dr. Rhonda Patrick, Dr. Derya Unutmaz presents an optimistic vision in which AI, biotechnology, and rapidly improving treatments help more people remain healthy long enough to benefit from the next generation of therapies.”

“High energy demand is a promising research setting. In a randomized crossover study of 15 healthy adults undergoing 21 hours of sleep deprivation, a single 0.35-gram-per-kilogram dose changed cerebral energy measures and improved selected cognitive outcomes.”

“A later crossover study using a lower weight-based dose found its clearest benefit in reasoning, while several memory, accuracy, fatigue, and sleepiness outcomes did not reliably improve. Routine muscle supplementation and acute sleep-loss research use different protocols.”

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”

“Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentially even muscle mass. She also discusses the profound effects of hyperthermic conditioning on the brain including cognitive function.”

“While ketogenic diets may not be optimal for adding muscle mass, they may be suitable for preserving muscle mass and improving other metabolic parameters, particularly during weight loss and fasting.”

“A recent study identified the branched-chain amino acid leucine as the primary amino acid sensor for mTOR. Interestingly, branched-chain amino acids have been favored by bodybuilders because of their ability to enhance muscle growth.”

“Thanks to Kyle and MedCram for having me for his interview. 00:58:31 - Rhonda's personal sauna protocol: duration, temperature, humidity, and frequency MedCram is a YouTube channel created by Kyle Allred, PA-C and Roger Sehuelt, MD, master educators of health and medical science.”

“A meta-analysis of resistance-training trials found that protein supplementation produced modest additional gains in strength and fat-free mass, with average fat-free-mass benefit plateauing near 1.62 g/kg/day. This is a group estimate, not a precise requirement for every older adult.”

“Observational physiology research from his group links more frequent lifelong endurance exercise with higher VO2 max and more favorable cardiovascular function, while stopping short of proving that one exact schedule is uniquely optimal.”