Related Episodes for Sleep deprivation leads to a preference for carbohydrates and sugary snacks | Matthew Walker

“Researchers treated patients with major depressive disorder with heat so that their core body temperature reached temperatures equivalent to those experienced with sauna use. Following just one treatment session, subjects experienced elevations in mood that lasted for several weeks.”

“Time-restricted eating, which involves taking in food within a specific period of the day and fasting for the remainder, can improve certain biomarkers of health - even without weight loss. One theory is that this eating pattern coordinates food intake with the body's peak metabolism period.”

“In a short controlled protocol in healthy young men, five nights of restricted sleep impaired glucose tolerance and muscle mitochondrial function, while participants who added high-intensity interval exercise did not show the same changes.”

“A 2025 meta-analysis found improved quality of life, no clear overall change in ejection fraction, and a borderline improvement in New York Heart Association functional class across a small set of trials.”

“In this Institute for Functional Medicine excerpt, Dr. Rhonda Patrick describes her personal 10–15-minute routine, usually five days per week: Tabata-style all-out efforts alternating with Zone 3 and sometimes Zone 2 recovery, plus resistance training.”

“Liberalizing the diet by altering protein, fat, and fiber intake may make the diet more tolerable. For those who have difficulty reaching and sustaining ketosis, ketone supplementation may be beneficial, but their use might interfere with weight loss.”

“But implementing a ketogenic diet is challenging. In this Aliquot, Dr. Dominic D'Agostino explains how to avoid side effects on a ketogenic diet, provides valuable pointers for success, and explains how the diet might help preserve muscle mass.”

“The “Big Mac effect”, a colloquial term coined by Ronald Krauss, refers to this negative impact, which may become the focus of a full-fledged nutritional research study once funding is available.”

“Recent human studies indicate that the fewer carbohydrates one eats, the lower the risk of death from all causes. In this clip, Dr. Eric Verdin explains the importance of the insulin signaling pathway in aging and highlights both animal and human research in this area.”

“A healthy immune system allows the body to fight bacterial and viral infections, as well as aberrant cells, which, left unchecked can progress to cancer. Insulin-like growth factor 1 (IGF-1) has some beneficial functions but is also known to promote the growth of existing cancer cells.”