Ranked by shared topics, with one result from each original episode.
“Whereas fasting turns off multiple pathways associated with aging, such as mTOR, IGF-1, growth hormone, and others, eating for optimal fitness activates these important processes. This Aliquot features Drs. Guido Kroemer, Dominic D'Agostino, Valter Longo, Peter Attia, and Rhonda Patrick.”
“In this Aliquot, clinical psychologist Dr. Ashley Mason and sleep expert Dr. Matt Walker describe some of the behaviors that can make getting a good night's sleep difficult – and how cognitive behavioral therapy and meditation can provide help.”
“The arrival of a new year is a great opportunity to make health-focused resolutions – promises to ourselves that we're going to live better, healthier, and (hopefully) longer. We all age at different rates, however, so our chronological age – the number of years we've lived – often differs from our biological age.”
“Regulating the amount of light in our environment is crucial for a good night's sleep and a good mood the next day. Habits such as using blue light-emitting electronics close to bedtime can reduce melatonin production by as much as 20 percent, impairing sleep.”
“Exercise is a huge driver of how well we age because it induces profound molecular shifts that support immune health and might even protect our telomeres – indicators of aging. Exercise might help forestall certain age-related diseases, such as Parkinson's disease, too.”
“Although alcohol may help us feel calm and ready to sleep, it has surprising effects on REM sleep and maybe our waking behaviors too. In this Aliquot, Dr. Matthew Walker, Tim Ferriss, and I discuss some of the risks and surprising effects of alcohol on human health and behavior.”
“Roughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for Alzheimer's disease. Many lifestyle behaviors can mitigate risk, especially sleep hygiene, which provides an opportunity to rid the brain of toxic metabolic byproducts that can contribute to Alzheimer's disease risk.”
“Naturally occurring forms of vitamin K include phylloquinone, known as vitamin K1, and a family of molecules called menaquinones, known as vitamin K2. In this Aliquot, Dr. Bruce Ames and I discuss the differences between (and dietary sources of) vitamins K1 and K2 and their effects on human health.”
“The benefits of HIIT include improvements in muscle tissue oxidative capacity, enhanced insulin response, improvements in heart function, and increased lactate – an important source of fuel for the heart, brain, and muscles.”
“Building muscle mass in one's early years is essential for staving off the age-related loss of muscle mass and may promote longevity. In this Aliquot, Dr. Stuart Phillips discusses the importance of building muscle through resistance training and why starting early is important.”