Related Episodes for Sulforaphane reduces DNA damage (in vivo vs. in vitro evidence) | Rhonda Patrick

“These transient stressors induce the expression of genes that process inflammatory molecules. In this clip, Tim Ferriss and Dr. Rhonda Patrick discuss acute versus chronic inflammation and how supplemental antioxidants can negate some of the benefits of exercise.”

“Even though the primary endpoints failed (NR did not improve insulin sensitivity or weight loss), he notes a meaningful signal in reduced liver fat—a 2% decrease in the NR group compared to a 0.2% reduction in the placebo group, a difference that didn't reach statistical significance, likely because subjects weren't randomized by liver fat and variability was high.”

“Dr. Rhonda Patrick discusses the differences between different forms of DHA in terms of bioavailability and transport into different cells. She talks about why a specific type of DHA (DHA in phosphatidylcholine) is more readily transported into the brain because it forms DHA-lysophsophatidylcholine.”

“In this clip, Dr. Ruth Patterson describes how eating following the body's circadian clock, eating during the day and fasting at night, enables the body to focus on repair rather than on the digestion of food.”

“Moreover, taking mega doses (i.e. 400 IU/day) of alpha tocopherol has the unintended side-effect of actually depleting tissue levels of another important form of vitamin E that plays an anti-inflammatory role, known as gamma tocopherol.”

“However, exercising while taking a non-steroidal anti-inflammatory agent (NSAID) may blunt the initial rush of acute inflammation and negate some of the long term health effects of exercise.”

“In this clip, Bruce Ames describes how folate is critical for the transferring of single-carbon groups between molecules. A deficiency in folate leads to errors in production of nucleic acids and can lead to double-stranded breaks in DNA.”

“Cells could be programmed to behave and function as they ordinarily would but with profound differences in their underlying code and translation apparatus, making them immune to all viruses and even horizontal gene transfer – a boon to preventing the unintentional spread of lab-produced genetics to wild-type organisms.”

“In this clip, Drs. Levine and Patrick discuss the epigenetic changes that occur with age, including methylation of CpG sites. Using methods discovered in recent research, the program of cellular aging may be reversible without disrupting cell function.”

“In this clip from Dr. Rhonda Patrick's appearance on Katie Couric's Next Question, she explains why magnesium supports both immediate energy needs and long-term cellular maintenance. Magnesium serves as a cofactor for more than 300 enzymes and helps maintain DNA structure, replication, and repair systems.”