Related Episodes for Could synthetic biology alleviate poverty? │ Dr. George Church

“Dr. Rhonda Patrick talks at SF Nerd Nite about transgenerational effects of caloric restriction on longevity, B-vitamins silencing bad genes, cognitive stimulation reversing neurodegenerative disease, exercise increases neurogenesis, and ways in which vitamin D might influence aging.”

“Although many seed vendors provide quality seeds that are free of pesticides and have high germination rates, determining the glucoraphanin content in broccoli seeds requires laboratory analysis that may be cost-prohibitive for most home growers.”

“Family-controlled research provides another view. A Swedish cohort of 2.48 million children found small associations in conventional models, but the estimates moved to the null when siblings with different prenatal exposure were compared.”

“In this talk, we’ll be exploring the intersection between genetics, nutrition, and environment: how your diet, micronutrients, exercise, heat stress, and sleep can change the expression of your genes and how this has profound effects on the way your body functions and ages.”

“However, a growing body of evidence suggests that pre-pregnancy health of both parents shapes the health of their offspring through epigenetic mechanisms, which are influenced by nutrition, stress, and other environmental factors.”

“Rumination, the practice of dwelling on external stressors to excess, can set in motion a cascade of hormonal and physiological responses that harm mental and physical health. Meditation has been shown to reduce rumination and its negative effects, however, and influences the gene expression of as many as 500 genes, many of which are in the brain.”

“Using a Mendelian randomization analysis, scientists determined that people carrying genetic variants associated with low vitamin D levels have higher mortality from respiratory tract infections and higher all-cause mortality.”

“Gene polymorphisms, small changes in an organism's DNA sequence, can affect the absorption and metabolism of nutrients, including vitamins and minerals. A polymorphism in the MTHFR gene that decreases enzyme activity leads to inefficient folate metabolism.”

“More than a century of research has demonstrated that nicotinamide adenine dinucleotide (NAD+) is an indispensable mediator of vital metabolic and physiological processes, including energy production, DNA synthesis and repair, and regulation of gene expression – across multiple species.”