Related Episodes for How Vitamin D Status Relates to Dementia Risk

“Controlled human studies support acute brain-related responses to high-intensity exercise. Six short all-out cycling intervals improved selected learning and executive measures while increasing circulating BDNF, IGF-1, and VEGF; lactate tracked several of these changes.”

“Dr. Patrick explains some of the early evidence that suggests the value prolonged fasting (48+ hours) may have from the standpoint of tissue rejuvenation and healthspan maintenance, as well as relevance for other more specific conditions.”

“In this clip, Dr. Valter Longo discusses the origin of the fasting-mimicking diet and a possible future which may lean away from a drug-centered mentality to one which allows the body to heal itself.”

“A large meta-analysis found that protein supplementation improved resistance-training gains in muscle size and strength, with little additional lean-mass benefit above an estimated total intake of about 1.6 grams per kilogram per day for most participants.”

“When produced during exercise (especially high intensity workouts like cycling, which shifts metabolism toward glycolysis to more quickly meet the high energetic demands), lactate switches on more than 600 genes involved in muscle adaptation, stimulates mitochondrial biogenesis – the process of making new mitochondria – and promotes protein synthesis, which is essential for muscle growth.”

“In this member Q&A clip, Dr. Rhonda Patrick shares four practices she uses or finds compelling for healthy aging: sauna, sulforaphane-rich foods or supplements, time-restricted eating, and high-intensity interval training.”

“In a secondary analysis of 72 men, the combined concentration of six PFAS declined by about 8 percent within the oat beta-glucan group over four weeks, while the study did not distinguish the magnitude of change from the control group.”

“Exposure to bright light also promotes the release of cortisol, and, in turn, the hormone drives wakefulness during the daytime hours. Chronic stress and mis-timed exposure to light can dysregulate cortisol release and promote aging, however.”

“High energy demand is a promising research setting. In a randomized crossover study of 15 healthy adults undergoing 21 hours of sleep deprivation, a single 0.35-gram-per-kilogram dose changed cerebral energy measures and improved selected cognitive outcomes.”

“A later crossover study using a lower weight-based dose found its clearest benefit in reasoning, while several memory, accuracy, fatigue, and sleepiness outcomes did not reliably improve. Routine muscle supplementation and acute sleep-loss research use different protocols.”