Related Episodes for What Five Days of High-Calorie Snack Overeating Did to Brain Insulin Signaling

“Dom's efforts at teasing out the differences between induced nutritional ketosis (through a low carbohydrate, high fat diet) and ketosis from the dietary introduction of exogenous ketones, like beta-hydroxybutyrate, especially in the context of therapeutic and performance enhancing effects.”

“Sprint-interval exercise improved reaction time on selected executive-function tasks for about 10 to 30 minutes in a controlled study, supporting Dr. Patrick's practice of using a short workout before an early talk or demanding meeting.”

“Dr. Patrick then prioritizes lower-glycemic-load, less-refined foods and adequate fiber. Early time-restricted eating can help some people reduce calories and may influence selected metabolic markers, but it is not required and must still preserve protein and diet quality.”

“Time-restricted eating can help some people reduce eating opportunities, although a 12-month trial found no additional weight or body-fat benefit when an eight-hour eating window was added to calorie restriction. Sleep also affects appetite and fat distribution.”

“Across standardized risk reductions, the models associated one vigorous minute with roughly 4.1 moderate minutes for all-cause mortality, 7.8 minutes for cardiovascular mortality, 5.4 minutes for major cardiovascular events, and 9.4 minutes for incident type 2 diabetes.”

“Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentially even muscle mass. She also discusses the profound effects of hyperthermic conditioning on the brain including cognitive function.”

“Inflammation, a downstream consequence of insulin resistance, promotes the formation of reactive oxygen species and other damaging molecules, which can enter the brain via the lymphatic system.”

Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX.

Dr. Michael Snyder discusses personalized medicine and the use of technologies that monitor metabolism and other health markers.

Dr. Ruth Patterson discusses the role of fasting in the prevention and survivorship of breast cancer.