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Found 108 matches across the FoundMyFitness library.

108 results

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TNF-alpha is a pro-inflammatory cytokine involved in systemic and brain-related inflammatory signaling. Elevated TNF-alpha commonly accompanies depression and is associated with depressive symptoms and changes in brain and neuroendocrine function; in mice with liver disease, brain…

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Caloric restriction

Jul 6, 2026

“"Those who attempted a 25% calorie-restricted diet for two years resulted in lower total cholesterol, LDL-cholesterol, triglycerides, C-reactive protein, TNF-alpha, and blood pressure even though they only were able to achieve 12% calorie-restriction.".”

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Toll-like receptors

Jun 6, 2025

“Elevated biomarkers of inflammation, such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha), are commonly observed in people with depression. These pro-inflammatory cytokines coincide with the development of depressive symptoms and induce changes in the brain and neuroendocrine function.”

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Quercetin

Jul 11, 2026

“Researchers investigated quercetin's capacity to decrease CRP, interleukin (IL)-6, and tumor necrosis factor-alpha (TNF-alpha). Analysis of six studies involving 348 participants revealed that quercetin reduced CRP in those over the age of 40 years, as well as those who had been diagnosed with a disease.”

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Science Digest

Probiotics may improve inflammation-associated behavioral changes in mice by lowering TNF-alpha blood levels. (2015)

Sep 9, 2022

“Mice that received the probiotics also had lower TNF-alpha levels and fewer activated immune cells in their brains compared to mice that received a placebo. These findings suggest that probiotics attenuate inflammation-associated sickness behaviors in mice, likely via modulation of the gut-brain axis.”

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Science Digest

Serotonin 5-HT2A receptor activation (molecular target of classical psychedelics) suppresses TNF-alpha-induced inflammation with extraordinary potency

Oct 25, 2017

“FTA: > We have now discovered that activation of 5-HT(2A) receptors in primary aortic smooth muscle cells provides a previously unknown and extremely potent inhibition of tumor necrosis factor (TNF)-alpha-mediated inflammation. [...] With the exception of a few natural toxins, no current drugs or small molecule therapeutics demonstrate a comparable potency for any physiological effect”

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Omega-3 fatty acids

Jul 20, 2026

“Participants also provided blood and saliva samples as a means to measure cortisol (a stress hormone), telomerase; anti-inflammatory cytokines, including interleukin (IL)-10 (IL-10); and proinflammatory cytokines, including IL-6, IL-12, and tumor necrosis factor-alpha (TNF-alpha).”

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