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“In a randomized crossover trial, a standardized ashwagandha extract produced a modest testosterone increase in overweight men with mild fatigue, while a meta-analysis of five tongkat ali trials found a positive pooled effect with substantial variation across studies.”

“Dr. Michael Grandner describes this as the "mind after midnight"— being awake past our normal bedtime biases us toward reward-seeking, negative affect, and weaker executive control, helping explain not only late-night eating (a preference for energy-dense, high-fat, and high-sugar foods) but other impulsive behaviors that occur at this time.”

“Davidson reported that five minutes of daily Healthy Minds Program practice for 28 days produced a significant decrease in interleukin-6 (IL-6), a pro-inflammatory cytokine, measured three months after the formal intervention ended and compared with an untreated control group.”

“In this Aliquot, Drs. Peter Attia, Stuart Phillips, Morgan Levine, Brad Schoenfeld, Michael Snyder, Valter Longo, Martin Gibala, George Church, as well as Kevin and Darya Rose and myself, share our strategies for finding our fitness.”

“From THC, CBD, alcohol, caffeine, and nicotine to melatonin, magnesium, glycine, and calming botanicals, these compounds can either support restorative sleep or subtly hijack it, changing REM, deep sleep, and circadian timing in ways we often do not feel until the next day.”

“Dr. Huberman connects that result with open questions about memory consolidation, trauma therapy, and recovery from sleep loss, while keeping those applications as research directions rather than established replacements for sleep.”

Click here to go to their Youtube page (https://www.youtube.com/c/Medcram) Dr. Roger Seheult is, as you will find out in the conversation, a boots on the ground, critical care pulmonologist. For him, COVID-19 is not just theory.

“It suggests that when the body runs low on essential vitamins or minerals, it doesn't distribute them evenly. Instead, it prioritizes urgent survival tasks, like keeping the heart beating or clotting blood, over long-term maintenance, such as repairing DNA or defending against oxidative damage.”

“In this Aliquot, I explain exactly what homocysteine is, how it impacts both cardiovascular and brain health, and how simple nutritional strategies—like supplementing with vitamins B6, B12, and methylfolate—can help bring levels down, supporting healthy aging and sharper cognitive function.”

“The physical activity guidelines and estimates on how much activity we need are heavily based on self-reported activity, which is useful but imperfect: people remember going for a run, but they forget the short, intense bursts in daily life like sprinting up stairs, chasing kids, and running to catch a bus.”