Search results for fasting

“For example, if basic research reveals that a particular diet is best for longevity, yet no long-lived populations around the world eat this way, then one may choose to be cautious about this diet. In this clip, Dr. Valter Longo discusses his new book "The Longevity Diet" and how his fasting-mimicking diet can treat or prevent several age-related diseases.”

“In this clip, Dr. Valter Longo describes how a fasting-mimicking diet can reduce markers of inflammation, such as C-reactive protein and Interleukin-6, possibly by killing damaged cells and regenerating others and resetting the system back to a more youthful state.”

“A ketogenic diet is high in fat, moderate in protein, and low in carbohydrates. Research shows that it mimics fasting by inducing metabolic switching – the capacity to shift from metabolizing glucose to metabolizing fatty acids.”

“Intermittent fasting (every other day) increased gut bacteria diversity and reduced inflammation, demyelination, and axonal damage in multiple sclerosis (MS) animal model. A small pilot trial in humans with MS showed many similar changes to the gut microbiome and blood adipokines such as leptin.”

“Then they infected the mice with a type of bacteria that commonly causes pneumonia to see how their immune systems responded. They found that after just four hours, the white blood cell numbers in the blood of fasting mice decreased by 90 percent, having accumulated in the bone marrow.”

“The study found that that mice that were fasted for 24 hours were less responsive to inflammatory pain compared to mice that did not fast. In addition to increasing many genes that are anti-inflammatory, the fasting also increased the production of a neurotransmitter, called NPY, which selectively blocks inflammatory pain responses.”

“Prior to this study, it was not known whether Oct4 was active in adult cells; however, these results show fasting or BHB administration activates youth-associated DNA factors that reduce senescence in mice and cell culture.”

“Exercising while fasted induces adaptations to mitochondria in muscle and adipose tissue including increased fatty acid metabolism that is blunted by pre-exercise feeding (meta-analysis of 46 clinical studies).”

“Fasting before exercise increased the expression of genes in adipose tissue that signify that stored fat is being used to fuel metabolism in overweight men but eating a meal 2 hours before did not. There was also greater fat oxidation (burning of fat) during exercise in the fasted state.”

“Dixit said it is well known that fasting and calorie restriction reduces inflammation in the body, but it was unclear how immune cells adapt to reduced availability of glucose and if they can respond to metabolites produced from fat oxidation.”