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“For an interesting discussion on the zinc ionophore activity of chloroquine in the context of coronavirus, watch coronavirus update #34 from Medcram on YouTube. Vitamin D and respiratory tract infections Vitamin D is a steroid hormone.”

“The analysis pooled data from 23 studies comprising 606 participants and determined the mean difference of neuromuscular performance (jump performance and sprint times), subjective measures of fatigue, muscle soreness, and biochemical markers, following either cold water immersion or passive recovery performed no less than 24-hours post-exercise stressor.”

“A non-invasive treatment of light and sound to increase brain waves known as gamma oscillations led to improvements in cognition and memory and a dramatic reduction in amyloid beta plaques in mice. Interestingly, some forms of meditation also increase gamma waves, particularly in advanced meditators.”

“Both light exposure and feeding time are well-known regulators of the circadian clock. Oxygen appears to function as a resetting cue for circadian clocks. Interestingly, the majority of modern commuter airplanes have a cabin oxygen pressure corresponds to ∼16% O2, which may actually aid in jet lag recovery.”

“Here’s an interesting report that didn't make it into this issue of the Digest. Micro- and nanoplastics are ubiquitous environmental pollutants. Humans encounter these pollutants through ingestion, inhalation, and skin contact, eliciting various harmful health effects. This review summarizes the current knowledge of the effects of micro- and nanoplastic exposure.”

“Allantoin is pretty interesting... in other studies, for example, it has been shown to significantly speed up skin wound healing. It's a common ingredient in some skin creams. While allantoin is commonly associated with comfrey, which contains it, comfrey also contains pyrrolizidine alkaloids that damage the liver and can lead to liver toxicity.”

“Here’s an interesting report that didn't make it into this issue of the Digest. Obesity and aging increase a person's risk of many diseases, including cardiovascular diseases and type 2 diabetes. This review presents the hypothesis that obesity accelerates the process of cardiac aging, exacerbating clinical outcomes of older adults with obesity.”

“Also interesting and from the article... > In addition to its pain modulating properties, GABA may also be capable of inhibiting inflammation. Recent studies have shown that immune cells called macrophages also possess GABA receptors. When these receptors were activated on the macrophages there was a decrease in the production of compounds responsible for inflammation.”

“Here’s an interesting report that didn't make it into this issue of the Digest. An abundance of evidence points to robust links between the gut microbiota and muscle mass and strength. This review describes these mechanisms and presents strategies for mitigating muscle loss in aging, including dietary fiber intake, pre- and probiotic intake, and exercise.”

Dr. Ruth Patterson discusses the role of fasting in the prevention and survivorship of breast cancer.