Search results for obesity

“Conventional health advice, such as healthy eating, physical activity, and education level are linked with slowed epigenetic aging, albeit weakly, and obesity, sleep deprivation, and smoking are linked with accelerated epigenetic aging.”

“Activating brown fat upon cold exposure may improve glucose and insulin sensitivity, increase fat utilization, and protect against diet-induced obesity. Studies in animals and humans have indicated that brown fat can improve glucose and insulin sensitivity, increase fat oxidation, and protect against diet-induced obesity.”

“Vitamin D, a fat-soluble nutrient, is sequestered in adipose tissue, limiting its circulation—an effect amplified in obesity. Obese adults, for example, exhibit a 57 % smaller rise in circulating vitamin D3 after whole-body ultraviolet exposure and are more than half as likely to reach sufficient vitamin D levels than normal-weight adults.”

“Muscle function Poor muscle strength and mass are linked with many health conditions, including obesity, diabetes, and chronic inflammation. When mice consumed diets that induced deficient, normal, or high levels of vitamin D, deficient mice had poor strength and low muscle mass.”

“Supplementing with 4,000 IU of vitamin D per day for 16 weeks reversed epigenetic aging by 1.85 years in overweight and obese African Americans that were low in vitamin D (randomized-placebo controlled trial). Epigenetic marks follow a certain pattern with age.”

“From the article: > Using technology that analyses 480 000 positions throughout the genome, they could see that epigenetic changes had taken place in 7,000 genes (an individual has 20-25 000 genes). They then went on to look specifically at the methylation in genes linked to type 2 diabetes and obesity.”

“Scientists have also identified interesting links between depression and obesity – likely mediated by elevated inflammation, since fat cells produce a wide array of inflammatory factors. In this Aliquot segment, psychiatrist Dr. Charles Raison describes the links between inflammation and depression.”

“As their use expands, researchers are exploring their potential beyond diabetes and obesity, including heart and kidney health and addiction treatment. But with their rise in popularity come important questions about long-term effects and safe use.”

“While BMI is a flawed method for measuring obesity, on a population level, most Americans that experience BMI increases are not doing so because they have been working hard to gain muscle (those individuals are the exception).”

“When mice consume a diet that is high in fat and sugar, they tend to develop metabolic diseases, such as obesity, diabetes, and cardiovascular disease, much like humans who eat a similar diet.”