Search results for stress

“Sulforaphane switches on the activity of a myriad of cytoprotective mechanisms, including Nrf2, a cellular protein that regulates the expression of antioxidant and stress response proteins.”

“Over years, the repeated pattern of "intermittent hypoxia"—oxygen drops followed by reoxygenation—creates oxidative stress that may accelerate neurodegeneration. Severe, untreated OSA is now recognized as a risk factor for conditions like Alzheimer's disease.”

“Each additional adverse event during childhood was associated with an 11% increased chance of shorter telomeres past age 50. Telomere length is a biomarker of healthy aging with shorter telomeres indicating accelerated aging. Lifestyle factors that have been shown to delay telomere shortening including physical exercise, vitamin D sufficiency, omega-3 fatty acid sufficiency, and meditation.”

“Dr. Mattson discusses the importance of alternating between periods of stress and recovery. After exposure to hormetic stressors such as exercise or fasting, periods of rest are necessary to build adaptations to the stress. For example, exercise increases muscle growth.”

“Learn more about this study which is now recruiting at UCSF in San Francisco. 00:33:37 - How the new sauna study will also be interrogating biomarkers thought to be implicated in adaptive responses to heat stress and exercise.”

“Perhaps the most clear-cut examples of cryotherapy’s beneficial effects are observed in the brain, where levels of the hormone and neurotransmitter norepinephrine – responsible for vigilance, attention, focus, and positive mood – increase markedly when the body is exposed to extreme cold.”

“The findings provide an early stress-specific signal, while routine dosing and the role of high-dose creatine during sleep loss still need larger trials. This clip is excerpted, with permission, from a conversation between Dr. Rhonda Patrick and Derek from More Plates More Dates.”

“How heat stress activates genetic pathways, including heat shock proteins, in worms and humans that lower protein aggregation and extend lifespan in worms. How too much iron can lead to protein aggregation and how vitamin D can prevent it.”

“The effects of heat stress on longevity have also been shown in lower organisms including flies and worms, increasing their lifespans by as much as 15 percent. The mechanism of lifespan extension was also teased out in these organisms and shown to be specifically dependent on heat shock proteins.”