Search results for blood-brain barrier

“While some forms of Parkinson's disease are genetic, most cases involve a complex interaction between genetic and environmental risk factors. In the early 1980s, intravenous drug users inadvertently injected a contaminated drug and developed parkinsonian symptoms overnight.”

“She talks about why a specific type of DHA (DHA in phosphatidylcholine) is more readily transported into the brain because it forms DHA-lysophsophatidylcholine. Krill oil and salmon roe both have a slightly higher concentration of DHA-lysophosphatidylcholine.”

“The brain makes some creatine locally and regulates entry from the blood through the blood-brain barrier. Dr. Candow therefore expects dose, duration, age, diet, and metabolic stress to influence how much supplemental creatine reaches brain tissue.”

“Exercise also reduced ambulatory blood pressure across randomized hypertension trials, supporting a role alongside usual care. During vigorous exercise, lactate acts as fuel and a signaling molecule. Dr. Patrick distinguishes human associations between exercise lactate and circulating BDNF or norepinephrine from animal evidence for direct brain BDNF effects.”

“Creatine plays a key role in maintaining cellular energy balance, and evidence suggests it can help the brain meet its high energy demands more efficiently. In Aliquot #131, The Muscle and Bone Benefits of Creatine, creatine expert Dr. Darren Candow and I discussed how creatine supplementation affects muscle quality, physical function, and even skeletal health, particularly in older adults.”

“There is so much to say when we talk about the NRF2 pathway and isothiocyanates like sulforaphane that we had to pack it into 47 minutes and break it into a few key sections. Key sections: For a more in-depth breakdown click the timeline link at the top of this page!”

“Human exposure reviews support ingestion and inhalation as important routes while emphasizing that measurement methods and health-effect estimates are still developing. Microplastics have been detected in human tissues, including recent postmortem brain samples.”

“Deep sleep activates glymphatic clearance of metabolic waste, while impaired brain glucose metabolism is one feature of Alzheimer's disease. APOE4 raises inherited risk, and Dr. Patrick emphasizes exercise, sleep, blood-pressure and weight control, and diet as modifiable factors.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Insulin-like growth factor 1 (IGF-1) promotes the growth of existing cancer cells and contributes to aging, but also has some beneficial functions. IGF-1 is required for the growth and repair of muscles and is also necessary for producing new brain cells.”