Search results for mortality

“Dose and retesting must account for baseline status and clinical context. A large randomized trial found that daily vitamin D supplementation did not reduce invasive cancer, major cardiovascular events, or all-cause mortality in generally healthy older adults.”

“VO2 max expresses how much oxygen the body can use during maximal exercise and is a direct measure of cardiorespiratory fitness. In a cohort of 122,007 adults referred for treadmill testing, higher fitness was associated with lower long-term mortality without an observed upper threshold of benefit.”

“Relevant publications Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies. Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses.”

“The evidence spans prevention, treatment tolerance, physical function, and survivorship. A meta-analysis of prospective studies in breast and colorectal cancer survivors associated higher post-diagnosis physical activity with lower total and cancer-specific mortality.”

“Earlier long-term research in older male physicians found no cognitive benefit, and the main COSMOS trial did not significantly reduce invasive cancer, cardiovascular events, or mortality over a median of 3.6 years.”

“Traditional Finnish sauna studies associate frequent sauna use with lower cardiovascular and all-cause mortality in observational cohorts. The practical question is the heat dose, not the label alone.”

“In a clinical referral cohort of more than 122,000 adults, lower treadmill fitness was strongly associated with higher long-term mortality, reinforcing the value of building fitness progressively. She also reviews a two-year randomized trial in healthy, sedentary adults around age 53.”

“Another is the GrimAge clock (named creatively for the Grim Reaper), which predicts lifespan and healthspan in units of years and tests whether potential lifestyle interventions may slow or reverse biological aging. A third clock, DNAm PhenoAge, predicts mortality risk among people of the same chronological age.”

“An individual-participant meta-analysis found increased mortality at low levels but did not establish a benefit for pushing concentrations to very high targets. Dr. Attia and Dr. Patrick then focus on trial design.”

“Studies using CT imaging associate higher visceral fat with insulin resistance and increased risks of cardiovascular disease, cancer, and mortality. Visceral fat can respond to changes in energy balance and physical activity.”