Search results for inflammation

“An enriched marine-oil study produced time- and dose-dependent increases in specialized pro-resolving mediators and altered blood-cell responses over 24 hours; it tested biomarkers, not disease prevention. Exercise, sauna, and cruciferous vegetables act through different pathways.”

“00:46:29 - The involvement of omega-3 derived signaling molecules called *specialized pro-resolving mediators, including molecules like the resolvins and maresins, in resolving inflammation. 00:48:50 - Differences in omega-3 DHA transport that may affect APOE4 carriers.”

“01:16:42 - Inflammation causes tryptophan – the precursor to serotonin – to be reallocated to kynurenine, which then turns into the neurotoxin quinolinic acid, leading to depression. Study. 01:18:00 - The many ways exercise and lifestyle can combat depression.”

“In fact, data from a 2017 study suggest that sauna use reduces the risk of developing certain chronic or acute respiratory illnesses, including pneumonia, by up to 40 percent. The sauna’s protective effects on the lungs might be due to reduced oxidative stress and inflammation associated with hyperthermia or direct beneficial effects on lung tissue.”

“Dr. Rhonda Patrick also describes observational reports linking coffee intake with DNA-methylation patterns and younger estimates from some epigenetic-aging measures. She connects these observations with possible effects on inflammation, metabolism, and gene regulation.”

“And omega-3s' anti-inflammatory qualities could play a role, too, especially in the setting of sarcopenia, where inflammation is a driver. Interestingly, some studies have shown that omega-3s work independently of their anti-inflammatory effects.”

“Dr. Patrick also connects meal size and fat composition with post-meal inflammation. In a randomized crossover trial, an omega-3-rich meal produced a different endotoxin and inflammatory response than saturated- and omega-6-rich meals.”

“Nrf2 regulates the expression of cytoprotective proteins that protect against oxidative stress due to injury and inflammation. Sulforaphane is the most potent naturally occurring inducer of Nrf2.”

“How this inhibition of class 1 HDACs leads to the increased expression of notorious longevity gene Foxo3, which may help explain why mice given an exogenous beta-hydroxybutyrate ester had lower markers of inflammation and oxidative damage, which are physiological contributors to the aging process.”

“A critical aspect of mitochondrial DNA release is the formation of pores created by the oligomerization of specific proteins called voltage-dependent anion channels (VDACs), which are found in the outer mitochondrial membrane.”