Q&A
Q&A #55: Red Yeast Rice vs. Statins—Cholesterol, Diabetes Risk, & Supplement Contamination
Dr. Rhonda Patrick explores iodine supplementation, choline & TMAO, curcumin safety, and red yeast rice in her latest Q&A.
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Q&A
Dr. Rhonda Patrick explores iodine supplementation, choline & TMAO, curcumin safety, and red yeast rice in her latest Q&A.
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“IGF-1 participates in a complex pathway known as the growth hormone/IGF-1 axis, where it exerts its role to accelerate aging. In this clip, Dr. Valter Longo explains how certain macronutrients influence the insulin/IGF-1/growth hormone axis to modulate aging in many cell types.”
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“Obesity promotes inflammation and elevated levels of the hormones estrogen and insulin, which may lead to an increased risk of breast cancer. Acting as growth factors, both estrogen and insulin can promote tumor cell growth, as well as undermine the innate defense system that removes damaged cells from the body.”
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“In the Diabetes Prevention Program, an intensive lifestyle intervention that included physical activity reduced progression to type 2 diabetes more than metformin among adults at high risk. The result shows how movement and weight-related behavior can change the course of prediabetes.”
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“Whether metformin reduces the risk of cancer in healthy people remains to be seen. In this clip, Dr. Rhonda Patrick describes the relationship between metformin and cancer incidence and the relevance for those with type 2 diabetes.”
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“Dr. Patrick also distinguishes general-population evidence from people with diabetes or insulin resistance, where some observational studies report different risk patterns and residual confounding remains substantial.”
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“A growing body of evidence suggests that metformin, a drug commonly used for the treatment of type 2 diabetes, is associated with a reduced risk of developing or dying from several types of cancer in adults with diabetes.”
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“Coffee has also been linked observationally to lower long-term type 2 diabetes risk. Acutely, however, caffeine can raise glucose or reduce insulin sensitivity in some people through sympathetic activation, so a short-term glucose response is not identical to the longer-term association.”
“Circadian rhythms play key roles in metabolic health and ultimately influence body weight, performance, and susceptibility to diseases like diabetes and cancer. Aligning food intake with circadian rhythms can improve many aspects of metabolic health.”
“Chronic inflammation plays a key role in the development of many chronic diseases, including cancer, cardiovascular disease, and diabetes. When it comes to managing inflammation, we often focus on what lifestyle habits we might need to get rid of, but it's just as important to focus on things we can add to our lifestyles.”
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