Search results for diabetes

“Chronic inflammation occurs on the cellular level in response to toxins or other stressors and is often “invisible.” It plays a key role in the development of many chronic diseases, including cancer, cardiovascular disease, and diabetes.”

“The two most regular sleep groups also had about 23% to 24% lower rates of death from cancer and about 31% to 38% lower rates of death from cardiovascular, diabetes-related, and other metabolic causes.”

“The findings demonstrated that each one-year increase in DNAm PhenoAge was associated with a 9 percent increase in all-cause mortality, a 10 percent increase in CVD-related mortality, a 7 percent increase in cancer-related mortality, a 20 percent increase in diabetes-related mortality, and a 9 percent increase in chronic lower respiratory disease mortality…”

“Insulin resistance and poor blood glucose control – defining characteristics of type 2 diabetes – drive changes associated with brain aging and cognitive decline. A growing body of evidence suggests that dementia is the manifestation of insulin resistance and altered metabolism in the brain.”

“Clinical studies have assessed the merits of sulforaphane in a wide range of chronic and infectious diseases, including autism, aflatoxin toxicity, air pollution detoxication, cancer, cardiovascular disease, diabetes, neurodegenerative disease, Helicobacter pylori infection, and many others.”

“Metabolic diseases, such as type 2 diabetes, cardiovascular disease, and non-alcoholic fatty liver disease (NAFLD), represent a major public health burden. Dietary factors such as excess sugar intake are associated with greater metabolic disease risk; however, it is unclear how different types of sugars (e.g., glucose, fructose, or sucrose) differentially impact metabolic health.”

“DNA damage occurs with normal metabolism and upon exposure to toxic environmental factors. It is associated with the development of some cancers, cardiovascular diseases, diabetes, and inflammatory bowel diseases.”

“Hyperglycemia, which occurs when glucose levels in the blood rise to dangerous levels, is a hallmark of diseases such as metabolic syndrome and type 2 diabetes. The effects of hyperglycemia are well documented and include cellular damage, inflammation, and pro-cancer effects; however, few studies have elucidated the cellular mechanisms of hyperglycemia.”

“Findings from a recent study demonstrate that ketones derived from medium chain triglyceride metabolism may provide an alternative fuel source for the brain in the setting of Alzheimer's disease. Ketones are molecules produced by the liver during the breakdown of fatty acids.”

“The mechanisms by which added sugars lead to metabolic diseases such as obesity, type 2 diabetes, cardiovascular disease, and fatty liver disease have been explored in research using mouse models; however, the dose of sugar used in these animal studies is usually much larger than what is normally consumed by people.”