Search results for GLP-1

Dr. Rhonda Patrick discusses her supplement routine, Neu5Gc risks, Repatha and diabetes, heat stress, osteoporosis in men, and plyometrics.

“In one US analysis, only 10.8% of people met the adequate intake for choline. A young-adult biomarker study found that 87% had serum alpha-tocopherol below a proposed adequacy threshold, but only 1% met its clinical-deficiency definition.”

“- Brady Holmer. Across different outcomes, the study found that 1 minute of vigorous activity typically matches 4–9 minutes of moderate activity. Specifically: All-cause mortality: 1 minute of vigorous = 4.1 minutes of moderate.”

“Manifold Bio - a biotech firm that specializes in protein "barcoding," a form of protein labeling, to facilitate protein therapeutics development.1. Rejuvenate Bio - a biotech company that is developing gene therapies designed to increase the health and lifespan.”

“Lutein and zeaxanthin also have evidence in age-related eye disease, although the AREDS2 trial did not find an additional reduction in progression to advanced macular degeneration in its primary comparison. Magnesium and creatine address different needs.”

“Dr. Patrick uses 4,000 IU of vitamin D as a reference point, which is also the adult tolerable upper intake level, and takes 250 milligrams of supplemental magnesium as her personal dose while emphasizing magnesium-rich foods.”

“You feel unrefreshed despite "enough" sleep, or your sleep feels shallow and fragmented. What sleep apnea does to your brain Beyond grogginess, untreated OSA changes the architecture of sleep itself—reducing restorative deep (slow-wave) and REM sleep, and leaving more time in light stage 1.”

“Just 20 grams of alcohol (about 1.5 standard drinks) can disrupt two key tight junction proteins known as zonula occludins-1 and occludin. These proteins are crucial for forming tight junctions that maintain intestinal barrier integrity.”

“During heat exposure, half to nearly three-fourths of the body's circulation shifts from the core to the skin to facilitate sweating. In a typical Finnish-style sauna session, for example, a person can expect fluid losses of one or two pounds (0.6 to 1.0 kilograms) per hour.”

“For example, growing up in an overly hygienic environment increases a child's risk for developing autoimmune diseases, but exposure to dirt, especially from soil, pets, and roaches, in the first year of life may provide protection against asthma and allergy-related skin disease.”