Search results for gut

“Urolithin A is a compound produced by certain gut bacteria from polyphenols found in foods like pomegranates, berries, and walnuts. It has attracted interest for its potential to activate mitophagy, the process cells use to clear out damaged mitochondria.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Oat beta-glucan can also serve as a fermentable substrate for the gut microbiome. Whole oats, oat bran, and standardized powders differ in beta-glucan dose and viscosity, so a product should state its beta-glucan content and ideally provide independent quality testing.”

“Coffee also has a reproducible relationship with the gut microbiome. An analysis that began with 22,867 people and extended across 211 cohorts found that coffee intake strongly tracked with Lawsonibacter asaccharolyticus.”

“Alcohol may also impair intestinal-barrier function and increase gut-derived inflammatory signaling, particularly with heavier use and alcohol-associated liver disease. The conversation also turns to phones and sleep.”

“Elevated gut serotonin promotes gut inflammation and is a common feature of inflammatory bowel diseases. Impaired gut barrier function drives intestinal permeability (also known as “leaky gut”) – a condition in which gaps form between the cells that line the gut.”

“Mice exposed to nanoplastics gained more weight than unexposed mice—about 28% more—despite no differences in liver or fat tissue mass. Nanoplastic exposure altered gut microbial populations, disrupted mucus production, and interfered with proteins maintaining the gut barrier.”

“On average, participants who ate the polyphenol-rich diet consumed 1391 milligrams of polyphenols per day, while those who ate a typical diet consumed only 812 milligrams of polyphenols per day. The study investigators noted that participants on the polyphenol-rich diet had higher levels of beneficial gut bacteria than those on the typical diet.”

“Butyrate supplementation also corrected abnormal tight junction proteins, improving barrier integrity and reducing gut inflammation. Learn more about butyrate in our overview article. Frequently Asked Questions Q: Are there supplements that help prevent leaky gut?”

“Aerobic exercise training increased butyrate-producing bacteria in the gut independent of diet. Time-restricted eating remodeled the gut microbiota, increasing the rate of butyrate production from bacteria such as Lachnospiraceae family.”