Search results for neurodegeneration

“While brain aging and neurodegeneration weren't the focus of the current study, multiple publications from the UK biobank have focused on these outcomes: Higher accelerometer-measured physical activity was associated with greater grey matter volume, most evident in adults 60 and older.”

“In this clip, Dr. Dale Bredesen talks about strategies for identifying the factors that contribute to one's risk of developing Alzheimer's disease and describes strategies for mitigating that risk.”

“An emerging strategy in the prevention and (possibly) treatment of neurodegenerative diseases is starving cells as a means to induce general autophagy to help rid the cell of protein aggregates.”

“Methyl patterns are crucial for a cell's maintenance of identity. As techniques are developed to differentiate and transdifferentiate cells from one cell type, such as a fibroblast, into another, such as a neuron, interesting patterns of effects on epigenetic age are revealed.”

“For example, if basic research reveals that a particular diet is best for longevity, yet no long-lived populations around the world eat this way, then one may choose to be cautious about this diet.”

“Severe sleep deprivation offers one such model. In a randomized crossover study of 15 healthy young adults, a single dose of 0.35 grams per kilogram changed brain-energy measures and reduced deterioration on selected cognitive tasks during about 21 hours awake.”

“Two such issues are blood flow reduction and blood-brain barrier leakage, which can be detected up to 10 years or more before cognitive decline, providing an opportunity for intervention with the right therapeutic approach.”

“A dose-response meta-analysis of 30 prospective studies, including more than 1.18 million participants, associated each additional daily cup with about a 6 percent lower incidence of type 2 diabetes, with similar patterns for caffeinated and decaf coffee.”

“There is so much to say when we talk about the NRF2 pathway and isothiocyanates like sulforaphane that we had to pack it into 47 minutes and break it into a few key sections. Key sections: For a more in-depth breakdown click the timeline link at the top of this page!”

“Other hormetic responses to cold exposure include increased production of PGC1-alpha, a protein that promotes mitochondrial biogenesis, the production of new, healthy mitochondria, and the activation of brown fat – a phenomenon once thought to occur only in newborns, but now known to occur in adults, especially after cold exposure.”