Search results for genetics

“They play an integral part in both tumor suppression and longevity. Four FOXO genes have been identified in mammals: FOXO1, FOXO3, FOXO4, and FOXO6. Due to specific genetic redundancies, FOXO2 is identical to FOXO3, and FOXO5 (an ortholog of FOXO3) is found only in fish.”

“Approximately 25 percent of people in the United States – roughly 75 million people – carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”

“Xenotransplantation, the practice of transplanting an organ from a non-human animal, such as a pig or chimpanzee, to a human, has its origins in the 1960s. Among six patients receiving kidney xenotransplants from chimpanzees in 1963, one survived for nine months in moderate health.”

“Many factors influence the risk for cardiovascular disease, including behavioral factors, such as diet, physical activity, and smoking status. Health parameters, including cholesterol, blood pressure, glucose control, weight, genetics, and age, also help stratify risk.”

“Researchers analyzed blood samples from 217 older men who had donated more than 100 times and compared them to 212 men who had donated fewer than 10 times. They looked for clonal hematopoiesis, a condition where blood stem cells acquire genetic changes that allow specific cell populations to expand.”

“Depression increases the risk of disease and death Several adverse medically and socially significant outcomes are associated with depression, which may elicit multigenerational effects due to genetic and epigenetic influences.”

“Telomerase enzyme activity is detectable in more than 85 percent of human cancers. Telomere length is profoundly influenced by the exposome, the totality of non-genetic exposures a person experiences during a lifetime.”

“Most common graying is strongly related to age and genetics, but selected observations suggest that stress, nutrient status, and cellular energy metabolism can influence pigment in some circumstances.”

“Rhesus monkeys share many genetic and physiological characteristics with humans and are good models for studying aging and disease in humans. Despite the critical differences in the findings from these studies, substantial evidence suggests that caloric restriction may serve as a means to increase human healthspan.”

“In this clip from Dr. Rhonda Patrick's appearance on The Tim Ferriss Show, she describes how baseline status, body size, genetics, sun exposure, and supplement content can contribute to that variation.”