Search results for genetics

“What is Alzheimer’s Disease? Alzheimer’s disease is a neurodegenerative condition characterized by the accumulation of amyloid-beta plaques, neurofibrillary tangles, and neurodegeneration. Genetics play an important role in Alzheimer’s disease.”

“Genetics plays an important role in longevity, but there is also a strong lifestyle component. Dr. Snyder's research, using deep molecular measurements, indicates that when you exercise, a profound molecular change occurs — particularly when it comes to immune molecules.”

“In this clip, Dr. Ruth Patterson discusses how healthful choices, such as even modest weight loss, can have beneficial effects that reduce the risk of breast cancer and a variety of other diseases.”

“Multiple sclerosis (MS) is an autoimmune neurodegenerative disorder that destroys myelin, the insulating layer that surrounds neurons. The causes of MS are complex and may arise from both genetic and environmental factors, including nutritional deficiencies.”

“Accelerated aging syndromes, such as Werner syndrome and Hutchinson-Gilford progeria syndrome, are characterized by genetic mutations that promote increased DNA damage, particularly at telomeres.”

“How heat stress activates genetic pathways, including heat shock proteins, in worms and humans that lower protein aggregation and extend lifespan in worms. How too much iron can lead to protein aggregation and how vitamin D can prevent it.”

“Approximately 25 percent of people living in the United States carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”

“Genetic predisposition, altered glucose uptake in the brain, high blood pressure, and other factors can weaken the barrier's integrity, allowing endotoxins and inflammatory immune cells to infiltrate the brain and increasing a person's risk for dementia.”

“The longevity-conferring effects of genetics, environment, and lifestyle appear to manifest early. For example, if a man has long sperm telomeres, his children will have long telomeres at birth.”

“Using a Mendelian randomization analysis, scientists determined that people carrying genetic variants associated with low vitamin D levels have higher mortality from respiratory tract infections and higher all-cause mortality.”