Search results for nrf2

“In this clip, Dr. Dominic D'Agostino explains the interrelationship between ketones and lactate as sources of energy for the brain and the role ketones may have in reducing oxidative stress through greater energetic efficiency.”

“How too much iron can lead to protein aggregation and how vitamin D can prevent it. A program, directed by Gordon, called the Caenorhabditis Intervention Testing Program which tests potential longevity compounds that may extend the lifespan of several different species of worms.”

“As discussed in Dr. Mattson’s review published in Scientific American, the benefit of vegetables is not to flood cells with antioxidants and eliminate all free radicals (which are important for normal cell signaling), but rather for phytochemicals to trigger the cell's own adaptive responses.”

“While Dr. Rhonda Patrick’s first video focused primarily on the micronutrients found in the various fruits and vegetables she put in her smoothie, this one, in addition to offering some modest changes on the recipe, instead focuses on the beneficial “hormetic” compounds that are NOT micronutrients.”

“Small trials in older adults and people with mild cognitive concerns have reported improvements in selected memory, processing-speed, or task-switching measures, although the response varies by study, product, population, and outcome.”

“The increased production of these genes is sustained over time – typically a period of days – so frequent, consistent consumption of foods and supplements that provide sulforaphane provides optimal exposure.”

“Sulforaphane promotes the production of glutathione by up-regulating enzymes necessary for its synthesis – and re-synthesis – making more glutathione available to the body's cells. And once glutathione is sacrificed and oxidized, it remakes it.”

“When cruciferous plants are crushed or damaged by insect attack or human consumption, the myrosinases hydrolyze the glucosinolates to yield a variety of degradation products, including isothiocyanate compounds.”

“The hydrolytic conversion of glucoraphanin to sulforaphane requires myrosinase, an enzyme co-located within the leaves, stems, and other components of the plants in which it is found. In humans, myrosinase-producing gut bacteria can convert unhydrolyzed glucosinolates to their cognate isothiocyanates, as well.”

“A growing body of evidence suggests that sulforaphane's protective effects extend to the brain, where it appears to enhance brain-derived neurotrophic factor (a protein that controls and promotes the growth of new neurons) and inhibits histone deacetylation (an epigenetic modification that influences gene expression).”