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“Exercise, weight management, tobacco avoidance, and alcohol reduction remain useful, but they complement rather than replace genetic counseling, enhanced surveillance, medication, or risk-reducing surgery when clinically indicated.”

“Dr. Brooks pairs these relationships with practiced coping methods such as therapy, prayer, meditation, or journaling, creating a practical framework for meeting both everyday stress and major life changes.”

“A meta-analysis of randomized trials found improvements in selected semen measures with some antioxidant and nutrient interventions, but formulations varied and pregnancy or live-birth outcomes were limited. More antioxidant is not always better.”

“The findings support working on several modifiable factors together, while leaving open how much each component contributes and whether these changes prevent an eventual Alzheimer's diagnosis.”

“Practical steps include avoiding tobacco, minimizing alcohol, maintaining a healthy weight, eating varied plant foods, exercising, using recommended vaccines and sun protection, knowing family history, and following age- and risk-based screening guidance.”

“In a small crossover trial involving people with insulin resistance, six one-minute intense intervals performed before the three main meals improved daily glucose control compared with one continuous 30-minute session.”

“Metformin, a drug commonly used to treat type 2 diabetes, has garnered interest as a longevity compound because it was shown to extend lifespan in some animal models. These effects are variable and seem to depend on the age and gender of the animals, as well as the dose provided.”

“Sulforaphane, an isothiocyanate compound derived from broccoli sprouts and certain cruciferous vegetables, exerts a wide range of beneficial effects in humans. Some of these effects are mediated by increased glutathione, one of the body's most potent antioxidants, to promote brain health.”

“In this Aliquot, Drs. Axel Montagne, Matthew Walker, Mark Mattson, Valter Longo, Peter Attia, and I discuss the risks associated with high blood pressure and describe some of the many ways lifestyle can help achieve and maintain healthy blood pressure.”

“A May 2025 Nature paper showed taurine uptake may fuel aggressive myeloid leukemias in laboratory and mouse models, illustrating how nutrients beneficial to healthy tissues may also feed certain cancers.”