FoundMyFitness library
Ranked by shared topics.
Small vessel disease is a generic term that describes dysfunction of blood vessels that occurs with aging and contributes to cognitive decline, cardiovascular disease, frailty, and stroke.
“Robust evidence from epidemiological, clinical, rodent, and in vitro studies has demonstrated that sulforaphane exhibits antioxidant and anti-inflammatory properties and may be beneficial against a wide range of chronic and acute diseases, including autism, cancer, metabolic dysfunction, and many others and may ameliorate some of the harmful effects associated with exposure to air pollution.”
“UPFs cause metabolic and cognitive changes in less than a week "...just 5 days of a high-calorie diet made the brains of these healthy, normal weight men structurally and functionally similar to people with obesity, and even after cutting the high-calorie foods out of their diet, these changes persisted for at least one week."”
“When adults with high blood pressure took cocoa flavonoid capsules (providing 862 milligrams of cocoa flavonoids) for eight consecutive days, their systolic blood pressure dropped by as much as 1.7 mmHg, and their pulse wave velocity decreased by as much as 0.14 m/s.”
“Drinking two to three cups per day is linked to roughly a 60% reduced risk of developing diabetes, a statistic that highlights coffee's robust metabolic benefits that arise from its ability to activate AMP-activated protein kinase (AMPK), a critical regulator of cellular energy metabolism.”
“Increased intestinal permeability (also known as "leaky gut") – a condition in which gaps form between the tight junctions that join enterocytes – allows pathogens to leak through the intestinal barrier and pass directly into the bloodstream, promoting inflammation through a specialized mechanism involving detection by toll-like receptors.”
“Insulin resistance in the brain is implicated in Alzheimer’s disease and is one reason why some researchers refer to the condition as “Type 3 diabetes.” Melatonin has been shown to enhance beta-cell function (the beta-cells are insulin-producing cells in the pancreas) and reduce the burden of beta-amyloid plaques and tau hyperphosphorylation in the brain of diabetic rats.”
“In a recent double-blind placebo-controlled trial involving 27 healthy older adults (average age, 62 years) with at least one risk factor for diabetes, each of the study participants engaged in three 45-minute aerobic exercise training sessions per week for 12 weeks using a treadmill, stationary cycle, or elliptical machine.”
“Another study in which 22 year old men who engaged in four weeks of high-intensity interval training three days a week and supplemented with 150 milligrams of resveratrol per day, the lowest dose of the studies mentioned so far, did not promote increases in the men's aerobic or anaerobic capacity, exercise substrate utilization, or muscle fiber-specific adaptations compared to exercise alone.”
“Interestingly, repeated exposure to whole-body heat treatment through sauna use has an even more profound effect on boosting growth hormone immediately afterward: Seventeen men and women who were exposed to two one-hour sauna sessions at 80°C (176°F) dry heat (typical Finnish-style sauna) per day for seven days exhibited a 16-fold increase in growth hormone levels by the third day.”