Ranked by shared topics, with one result from each original episode.
“Whereas fasting turns off multiple pathways associated with aging, such as mTOR, IGF-1, growth hormone, and others, eating for optimal fitness activates these important processes. This Aliquot features Drs. Guido Kroemer, Dominic D'Agostino, Valter Longo, Peter Attia, and Rhonda Patrick.”
“The arrival of a new year is a great opportunity to make health-focused resolutions – promises to ourselves that we're going to live better, healthier, and (hopefully) longer. We all age at different rates, however, so our chronological age – the number of years we've lived – often differs from our biological age.”
“Diet stands out as low-hanging fruit for influencing our lifespan. Optimizing macronutrient intake, practicing time-restricted eating, and consuming healthful bioactive compounds are critical aspects of a healthy diet. In part II of this two-part Aliquot, Drs.”
“Since then, the body of research enumerating the profound anti-inflammatory and generalized health-promoting qualities of omega-3s continues to grow; however, some studies fail to show any effects from omega-3 supplementation.”
“A healthy intestinal barrier limits the transport of pathogens and endotoxins from the gut to the bloodstream; however, increased gut permeability (known as "leaky gut") raises endotoxin levels, leading to metabolic endotoxemia.”
“Exercise is a huge driver of how well we age because it induces profound molecular shifts that support immune health and might even protect our telomeres – indicators of aging. Exercise might help forestall certain age-related diseases, such as Parkinson's disease, too.”
“But could aging become reversible in the future? Technologies like interrupted cellular reprogramming, in combination with future advances in the field of epigenetics, offer the promise that scientists may eventually be able to develop the means to reverse aging.”
“Roughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for Alzheimer's disease. Many lifestyle behaviors can mitigate risk, especially sleep hygiene, which provides an opportunity to rid the brain of toxic metabolic byproducts that can contribute to Alzheimer's disease risk.”
“Non-steroidal anti-inflammatory drugs, or NSAIDs, are among the most widely used drugs worldwide, available in both prescription and over-the-counter forms, such as aspirin, ibuprofen, naproxen, and others.”
“The benefits of HIIT include improvements in muscle tissue oxidative capacity, enhanced insulin response, improvements in heart function, and increased lactate – an important source of fuel for the heart, brain, and muscles.”