Related Episodes for Toll-like receptors

“Your skin is a crucial barrier to the outside world – the first line of defense against environmental exposures, and the primary means by which the body retains fluids necessary for survival. Consequently, maintaining a healthy skin barrier is important for your overall health. In this Aliquot, Dr. Patrick describes some things you can do to protect your skin.”

“Advanced glycation end-products, or AGEs for short, are created when the sugars, amino acids, and fats in food encounter heat. AGEs also form in the body during normal glucose metabolism. However, if high levels of AGEs accumulate in the tissues and blood, they can become pathogenic.”

“Preventing dementia requires a lifelong and multipronged approach that involves keeping inflammation (and its aging effects) at bay and making healthy lifestyle choices, such as exercising and consuming omega-3 fatty acids.”

“Genetic predisposition, altered glucose uptake in the brain, high blood pressure, and other factors can weaken the barrier's integrity, allowing endotoxins and inflammatory immune cells to infiltrate the brain and increasing a person's risk for dementia.”

“Berberine is a plant-derived compound that may be beneficial for treating a wide range of chronic health conditions associated with obesity, such as hypertension, dyslipidemia, and type 2 diabetes, among others.”

“Sulforaphane, a bioactive compound derived from broccoli, broccoli sprouts, and red kale, exerts potent antioxidant and anti-inflammatory properties that can combat various chronic and acute diseases.”

“As research progresses, my dietary and supplement habits adapt. At times, it's the ineffable quality of consciousness, submerged in a mental calculus of cost-benefits, that nudges a change of heart. Other times, it's the stark contradiction of new data that compels a shift.”

Hormesis is a compensatory defense response to a stressor that conditions the body against future stressors. Heat exposure – from sauna use, hot tubs, or eve...

“Early biomarkers of vascular dysfunction, such as soluble platelet-derived growth factor receptor-beta (sPDGFR-β), can help identify individuals at risk for developing Alzheimer's disease. These biomarkers are being validated on high-throughput platforms for large-scale testing.”

“While sanitation and clean drinking water are critical to survival, the over sterilization of our environment may play a role in modulating the human immune system. In this clip, Dr. Charles Raison highlights how ancient practices such as heat exposure, long-distance running, and fasting may promote well-being in the modern world.”