Related Episodes for Chris McGlory, PhD, on the Anabolic Potential of Omega-3 Fatty Acids

“Creatine works by building tissue stores, so consistent daily intake matters more than taking it immediately before a specific workout. Dr. Patrick and Dr. Candow also discuss its value during aging, when preserving training quality and muscle becomes increasingly important for function and independence.”

“00:20:21 - Some of the key blood-based biomarkers that are useful for tracking and projecting future cognitive health, including: homocysteine (<7μml/L preferred), which Dr. Bredesen indicates may be a mediator of cerebral atrophy, and also fasting insulin (<5% preferred), hemoglobin A1c, fasting glucose, vitamin D, and a number of other hormones relevant for trophic support.”

“A critical element in healthiness is the timing and content of our meals. Time-restricted eating, a form of daily fasting wherein the time of the day during which a person eats is limited, capitalizes on the body's natural circadian metabolic rhythms to promote health.”

“The impact of the ketogenic diet on gut bacteria has not been actively studied. In animal models high-fat diets are thought to provoke the release of endotoxin from bacterial cell membranes resulting in negative health consequences. In this clip, Dr. Dominic D'Agostino and Dr. Rhonda Patrick discuss the ketogenic diet and its implications for gut health.”

“For example, if basic research reveals that a particular diet is best for longevity, yet no long-lived populations around the world eat this way, then one may choose to be cautious about this diet.”

“Lunch varied among sardines, mackerel, wild salmon, avocado, nuts, fruit, cheese, and quinoa salad, giving her flexible sources of protein, marine fats, fiber, and fermented foods. Dinner typically paired fish, chicken, or occasional beef with vegetables or salad.”

“Patients assigned to supervised exercise during neoadjuvant chemoradiation, followed by continued activity before surgery, were more likely to achieve a complete or near-complete pathological response than those receiving usual care.”

“A larger randomized-trial meta-analysis also found modest average reductions in BMI, waist circumference, and body-fat percentage, although protocols and populations varied. These averages do not mean that HIIT alone guarantees fat loss.”

“The physical activity guidelines and estimates on how much activity we need are heavily based on self-reported activity, which is useful but imperfect: people remember going for a run, but they forget the short, intense bursts in daily life like sprinting up stairs, chasing kids, and running to catch a bus.”

“Dr. Patrick describes increased shear as a possible way vigorous exercise can damage fragile circulating tumor cells; this is a proposed mechanism, not proof that a workout eliminates metastasis or treats an established tumor.”