Related Episodes for Wim Hof’s personal connection to depression and the historical use of cold as a treatment

“Among the 12 participants who completed the final assessment in this single-arm feasibility study, the mean Beck Depression Inventory-II score fell by 15.8 points, and 11 no longer met criteria for major depressive disorder.”

“Circulating LPS can also bind to lipoproteins, facilitating their absorption in the liver during LDL recycling, effectively removing LPS from circulation and lowering systemic inflammation – a phenomenon demonstrated mechanistically with statins that increase lipoprotein recycling by increasing LDL receptors.”

“00:34:40 - Repeated traumatic brain injury has cumulative neuroinflammatory effects in the brain over years, including amyloid-beta plaque and tau tangle formation. Study. 00:44:00 - A variant of the APOE gene increases risk of developing Alzheimer’s disease as much as 15-fold.”

“New Scientist article. 02:06:10 - Some people, like Tom Cruise and Keanu Reeves, seem to defy aging. 02:08:15 - One 12-ounce can of sugar-sweetened soft drink per day shortened telomere length, corresponding to 4.6 years of biological aging.”

“Dr. Patrick also discusses glucose, HbA1c, fasting insulin, kidney and electrolyte markers, hs-CRP, fibrinogen, thyroid tests, CBC, vitamin D, sex hormones, IGF-1, and the Omega-3 Index.”

“Because red blood cells turn over slowly, the test provides a longer-term view of marine omega-3 status than a recent meal and gives people a measurable way to evaluate diet or supplementation.”

Click here to go to their Youtube page (https://www.youtube.com/c/Medcram) Dr. Roger Seheult is, as you will find out in the conversation, a boots on the ground, critical care pulmonologist. For him, COVID-19 is not just theory.

“The mast cells release pro­inflammatory cytokines and proteases that damage the gut, leading to intestinal permeability, a condition otherwise known as “leaky gut.” This leakiness allows bacteria and bacterial antigens to cross the gut’s inner layer, the epithelium, and activate even more immune cells, leading to more inflammation – a key driver in the aging process.”

“More than a century of research has demonstrated that nicotinamide adenine dinucleotide (NAD+) is an indispensable mediator of vital metabolic and physiological processes, including energy production, DNA synthesis and repair, and regulation of gene expression – across multiple species.”

“EPA and DHA play particularly important roles in heart health because they participate in pathways involved in the production of hormones that regulate blood clotting and inflammation, help maintain healthy heart rhythms, and influence the contraction and relaxation of arteries.”