Related Episodes for A diminished interferon response drives poor outcomes in COVID-19 | Roger Seheult

“Exercise studies also show that prolonged endurance work can lower circulating glutamine and alter immune measures, which helps explain interest in supplementation during heavy training.”

“In an early randomized workplace study, healthy employees who completed an eight-week mindfulness program showed a greater rise in antibodies after influenza vaccination than a waitlist group.”

“A meta-analysis of 49 studies involving 1,863 adults found that protein supplementation during prolonged resistance training produced additional gains in one-repetition maximum strength, fat-free mass, and muscle size compared with training alone.”

“In a randomized crossover trial, a standardized ashwagandha extract produced a modest testosterone increase in overweight men with mild fatigue, while a meta-analysis of five tongkat ali trials found a positive pooled effect with substantial variation across studies.”

“Randomized trials and a meta-analysis show that at least three grams of oat beta-glucan per day can lower LDL by about five to seven percent, with high-molecular-weight products producing the most consistent effects.”

“In a randomized factorial design, participants were assigned to one gram per day of algae-derived omega-3 or placebo, 2,000 IU of vitamin D3 or placebo, and a 30-minute home strength program three times weekly or a flexibility control.”

“Melatonin appears in the comparison as a personal, goal-specific choice rather than a universal nightly supplement. Dr. Patrick also discusses glycine, collagen, myo-inositol, and other non-overlapping items with different levels of evidence.”

“Some research suggests that dietary supplements might offer a means to lengthen telomeres. Candidates include vitamin D, omega-3 fatty acids, and TA-65, a product that purportedly contains extracts of astragalus membranaceus, a plant-based compound that demonstrates anti-aging effects.”

“A second randomized trial found that a single vitamin D3 dose taken with food increased vitamin D status, with a larger rise when the meal contained at least 15 grams of fat. These findings support taking vitamin D with a meal that contains some fat.”

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”