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Related Episodes for The evolutionary origin of hormesis | Dr. Mark Mattson

Ranked by shared topics, with one result from each original episode.

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How Stress Can Change Magnesium Balance

Mar 29, 2024

“In a placebo-controlled study of eight healthy adults, adrenaline infusion lowered plasma magnesium, and levels had not recovered one hour later. Investigators proposed a shift into cells after beta-adrenergic stimulation; the study did not measure cortisol, urinary loss, total-body depletion, or clinical deficiency.”

magnesium exercise sleep stress
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242
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Episode

Sulforaphane and Its Effects on Cancer, Mortality, Aging, Brain and Behavior, Heart Disease, & More

Dec 14, 2016

“There is so much to say when we talk about the NRF2 pathway and isothiocyanates like sulforaphane that we had to pack it into 47 minutes and break it into a few key sections. Key sections: For a more in-depth breakdown click the timeline link at the top of this page!”

sulforaphane brain cancer aging
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243
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What Alpha-Lipoic Acid Does in Metabolism

Jan 22, 2025

“Human trials suggest that alpha-lipoic acid can modestly improve selected lipid measures. A dose-response meta-analysis of 12 studies found reductions in total cholesterol, LDL cholesterol, and triglycerides across doses from 300 to 1,200 milligrams per day.”

supplements metabolism cholesterol mitochondria
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244
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Episode

Dr. Terry Wahls Discusses Her Multiple Sclerosis Protocol

Jul 22, 2014

“In this video, Dr. Rhonda Patrick interviews Dr. Terry Wahls about how she reversed her secondary-progressive multiple sclerosis with a micronutrient-dense diet and Paleo principles.”

nutrition brain diet epigenetics
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245
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The Two-Year Exercise Program That Reduced Heart Stiffness

May 27, 2026

“During the peak phase, participants sometimes completed two interval sessions per week, while the longer maintenance phase generally used one interval session alongside continuous endurance work and strength training.”

exercise aging performance aerobic
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246
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Two-decade phytochemical expert Dr. Jed Fahey responds to carnivore doctor’s rant | Jed Fahey

Dec 3, 2020

“Robust scientific evidence indicates that consuming a plant-rich diet that provides vitamins, minerals, fiber, and phytochemicals is healthier than consuming an all-meat diet. In this clip, Dr. Jed Fahey rebuts popular claims that an all-meat diet is healthful.”

sulforaphane diet autism isothiocyanates
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247
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Episode

Vitamin C: Oral vs. Intravenous, Immune Effects, Cancer, Exercise Adaptation & More

May 12, 2020

“Since then, countless studies have tested Pauling's theories about vitamin C, colds, and cancer (and many others), and a substantial body of evidence has emerged, identifying critical roles for vitamin C in immune function, cardiovascular and respiratory health, cognitive development and preservation, and many other aspects of human health.”

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248
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What a New Creatine Trial Really Measured

Mar 31, 2025

“A meta-analysis restricted to direct regional measures from MRI, CT, or ultrasound found a very small average hypertrophy benefit when creatine was combined with resistance training, with uncertainty around the pooled estimate and variation across sites and populations.”

exercise performance muscle strength
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249
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What Urolithin A May Offer for Muscle and Mitochondrial Health

Sep 14, 2026

“In a four-month randomized trial of 88 overweight, untrained middle-aged adults, daily doses of 500 or 1,000 milligrams improved some muscle and mitochondrial measures, while the primary outcome of peak power did not significantly improve.”

microbiome performance mitochondria rhonda
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250
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Episode

Can exercise replace alcohol cravings?

Nov 2, 2022

“Longer endurance aerobic exercise seems to be most effective at producing higher levels of FGF21, coinciding with anecdotes you might have heard from runners who have successfully used exercise in this sort of way. Relevant publications Flippo, Kyle H., et al.”

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