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Related Episodes for Exercise as a Treatment for Depression

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How to Build Muscle With a Nutrient-Dense Surplus and Quality Protein

May 6, 2024

“A large meta-analysis found that protein supplementation improved resistance-training gains in muscle size and strength, with little additional lean-mass benefit above an estimated total intake of about 1.6 grams per kilogram per day for most participants.”

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132
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Dr. George Brooks on Lactate Shuttle Theory, Relevance for Traumatic Brain Injury, & More

Dec 3, 2014

“When produced during exercise (especially high intensity workouts like cycling, which shifts metabolism toward glycolysis to more quickly meet the high energetic demands), lactate switches on more than 600 genes involved in muscle adaptation, stimulates mitochondrial biogenesis – the process of making new mitochondria – and promotes protein synthesis, which is essential for muscle growth.”

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A Practical Hierarchy for Lowering Glucose and HbA1c

Sep 12, 2024

“Dr. Patrick then prioritizes lower-glycemic-load, less-refined foods and adequate fiber. Early time-restricted eating can help some people reduce calories and may influence selected metabolic markers, but it is not required and must still preserve protein and diet quality.”

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Why Evidence for Grounding and Inflammation Remains Limited

Dec 4, 2024

“For people seeking better-supported ways to improve inflammatory health, she points to regular exercise, marine omega-3 intake, and sulforaphane-rich foods as practical areas with a larger human evidence base.”

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135
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Episode

"Hacking Your Genes" at SF Nerd Nite

Nov 8, 2017

“Dr. Rhonda Patrick talks at SF Nerd Nite about transgenerational effects of caloric restriction on longevity, B-vitamins silencing bad genes, cognitive stimulation reversing neurodegenerative disease, exercise increases neurogenesis, and ways in which vitamin D might influence aging.”

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Four Practices Dr. Rhonda Patrick Uses to Support Healthy Aging

Dec 12, 2024

“In this member Q&A clip, Dr. Rhonda Patrick shares four practices she uses or finds compelling for healthy aging: sauna, sulforaphane-rich foods or supplements, time-restricted eating, and high-intensity interval training.”

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137
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Episode

How Heat Therapy Improves Slow Wave Sleep

May 30, 2023

“Translating sleep insights into practical steps These findings highlight the possibility of using heat therapy or vigorous exercise to influence slow-wave sleep, drawing on the interplay between body temperature regulation, immunity, physical activity, and hormones.”

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138
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History and discovery of longevity genes | David Sinclair

Nov 7, 2019

“More than four decades of study in the field of aging research have yielded some impressive findings, the most significant of which was the identification of longevity genes that are present in nearly every life form on earth.”

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How a Two-Year Exercise Program Improved Heart Fitness

Jun 24, 2026

“In this clip from Dr. Rhonda Patrick's conversation with Derek from More Plates More Dates, she explains how progressive endurance training can improve VO2 max and the heart's ability to fill with blood.”

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How Creatine Supports Exercise and Brain Energy

Sep 17, 2025

“A single 0.35-gram-per-kilogram dose of creatine monohydrate, equal to 24.5 grams for a 70-kilogram adult, reduced fatigue and improved word memory and processing speed on selected tasks versus placebo. It also changed brain-energy measures.”

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