Related Episodes for How a Daily Multivitamin Affected Cognition and Epigenetic Aging

“The majority of glutamine administered orally is taken up by the liver and gut, with little ending up in the bloodstream. Dr. D'Agostino discourages supplementing with glutamine for patients with cancers of the gastrointestinal tract and even recommends they avoid high glutamine containing foods.”

“In this short video, Rhonda talks about the new study and suggests that if you prefer your cruciferous veggies steamed, sautéed, or roasted, this strategy might offer a way to have your cooked vegetables and get your sulforaphane, too.”

“If you have used a consumer genetic testing service like 23andMe or AncestryDNA and want to learn more about whether or not the data indicates your specific genotype on these SNPs, check out our free viral report here.”

“The most compelling human signal appears when the brain is under acute strain. In a randomized crossover study, a single dose of 0.35 grams per kilogram during 21 hours of sleep deprivation changed cerebral energy metabolites and preserved selected measures of cognitive performance.”

“A separate six-week randomized study in 30 healthy young adults found that neither 10 nor 20 grams per day improved the tested cognitive outcomes compared with placebo. The result is an important counterweight to the acute sleep-deprivation experiment.”

“00:20:21 - Some of the key blood-based biomarkers that are useful for tracking and projecting future cognitive health, including: homocysteine (<7μml/L preferred), which Dr. Bredesen indicates may be a mediator of cerebral atrophy, and also fasting insulin (<5% preferred), hemoglobin A1c, fasting glucose, vitamin D, and a number of other hormones relevant for trophic support.”

“A critical element in healthiness is the timing and content of our meals. Time-restricted eating, a form of daily fasting wherein the time of the day during which a person eats is limited, capitalizes on the body's natural circadian metabolic rhythms to promote health.”

“Tools, companies, and resources mentioned OpenAI - AI research and deployment company behind widely used GPT systems and developer tools; its science case study describes GPT-5 helping Unutmaz's lab resolve a long-standing immunology question.”

“Dr. Rhonda Patrick discusses the differences between different forms of DHA in terms of bioavailability and transport into different cells. She talks about why a specific type of DHA (DHA in phosphatidylcholine) is more readily transported into the brain because it forms DHA-lysophsophatidylcholine.”

“Dr. Patrick explains that she uses zinc lozenges only during exposure or the earliest signs of illness, often totaling roughly 80 to 100 milligrams per day for a short period. Small randomized zinc-acetate lozenge trials have produced mixed results, with one reporting a shorter cold and another finding no faster recovery with more adverse effects.”