Related Episodes for How Lactate Links Vigorous Exercise to Brain Health

“In more than 2,000 adults ages 51 to 80, higher Sitting-Rising Test scores were associated with longer survival, making floor-transfer ability a useful marker of functional capacity. Floor time can include cross-legged sitting, kneeling, side-sitting, or sitting with the legs extended.”

“Dr. Schoenfeld says the situation is likely more complex and nuanced. For example, a marathon runner will have difficulty with hypertrophy, probably due to overtraining rather than intracellular signaling negatively affecting muscle development.”

“A growing body of scientific evidence suggests that there's a correlation between nutrition, exercise, sleep, and stress management and having longer telomeres. Identifying the mechanisms that drive these correlations has proven challenging, but a few candidates stand out, including improvements in immune function and metabolic health.”

In this clip, Dr. Patrick explains how intense exercise beneficially alters tryptophan and kynurenine metabolism in a way that may benefit depression.

“Dr. McGlory sheds light on the relationship between aerobic conditioning and muscle hypertrophy, addressing the notion that aerobic exercise might hinder muscle growth gained through resistance training.”

“The fact that poor sleep is linked with the aggregation of amyloid-beta plaques in the brain and Alzheimer's disease is not surprising. Although some strategies for improving the quality of sleep among people with Alzheimer's have been identified, this might be too late to turn the tide of cognitive decline.”

“Removing former drinkers from the non-drinker category reveals a different story: One study observed that the lowest risk for cardiovascular disease (i.e., ischemic heart disease) was right below one standard U.S. drink per week — men and women at this level of consumption had an ~18% lower risk compared to nondrinkers.”

“Dr. Huberman’s practical range is deliberately cautious: not drinking avoids the exposure, and lower weekly intake creates less burden than a drink every night or heavier episodes.”

“Vasopressin, a pituitary hormone that acts to promote the retention of water by the kidneys and increase blood pressure, is also a social bonding hormone in males — similar to oxytocin in females. Tim recounts his experiences taking vasopressin in college to boost his short term memory.”

“Sulforaphane, an isothiocyanate compound derived from broccoli sprouts and certain cruciferous vegetables, exerts a wide range of beneficial effects in humans. Some of these effects are mediated by increased glutathione, one of the body's most potent antioxidants, to promote brain health.”