Related Episodes for Immune stimulation may treat depression via cytokines that boost neurotrophic factors | Charles Raison

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

“Not only is salmon roe a good source of DHA, it also provides protein, vitamins, minerals, and astaxanthin – an antioxidant compound that gives salmon its reddish or pinkish tint. In human studies, astaxanthin reduces biomarkers of oxidative stress.”

“Although the findings of a large meta-analysis published in the journal Annals of Internal Medicine indicated that there was no evidence to support the notion that consumption of saturated fat increased the risk of heart disease, the studies on which their conclusions were based were primarily observational.”

“Compared with one sauna session per week, four to seven weekly sessions were associated with 66% lower dementia hazard and 65% lower Alzheimer's disease hazard, showing a strong dose-related pattern in this population. A second Finnish cohort followed 13,994 men and women.”

“A systematic review and meta-analysis of 44 randomized trials found that berberine improved several surrogate measures, including inflammatory biomarkers, stroke-related neurological deficit scores, and carotid intima-media thickness.”

“In this video, Dr. Rhonda Patrick interviews Dr. Terry Wahls about how she reversed her secondary-progressive multiple sclerosis with a micronutrient-dense diet and Paleo principles.”

“Dr. Patrick links hypertension with cardiovascular disease and dementia risk and emphasizes magnesium-rich foods within a DASH-style pattern, including leafy greens, legumes, nuts, and whole grains. A meta-analysis found modest average blood-pressure reductions with supplemental magnesium.”

“Dr. Panda discusses the effects of time-restricted feeding on systemic inflammation; time-restricted eating as an opportunity for night-time repair that may prevent intestinal hyperpermeability (i.e., leaky gut), a primary source of systemic inflammation; and how the timing of macronutrients may differentially affect gut permeability.”

“Early human evidence includes local-heat studies during limb immobilization and biomarker studies after resistance training, but those results do not prove that whole-body sauna builds muscle or prevents age-related muscle loss.”

“A national survey analysis estimated 2.6% severe deficiency, 22% moderate deficiency, and 40.9% insufficiency among US adults, although prevalence changes with the threshold used. These categories should remain distinct because insufficiency is not the same as clinical deficiency.”