Episode archive

Posted on June 10th 2024 (7 days)

Dr. Andrew Huberman discusses the role of dopamine in driving motivation and offers practical tools for enhancing mood and focus.

Posted on May 27th 2024 (21 days)

Dr. Levine details his research findings that show how a structured exercise regimen can reverse up to 20 years of heart aging.

Posted on December 27th 2023 (6 months)

Dr. Peter Attia presents practical steps we can implement to improve our health, emphasizing the importance of each aspect while providing actionable advice.

Posted on September 19th 2023 (9 months)

Dr. Martin Gibala discusses HIIT's health benefits and describes common HIIT protocols.

Posted on July 3rd 2023 (12 months)

Dr. Chris McGlory discusses muscle protein dynamics, emphasizing how omega-3 helps maintain muscle mass in older adults.

Posted on February 27th 2023 (over 1 year)

Dr. Axel Montagne discusses blood-brain barrier dysfunction in dementia and early-stage age-related cognitive decline.

Posted on December 6th 2022 (over 1 year)

Dr. Brad Schoenfeld studies the importance of resistance exercise in maintaining muscle mass.

Posted on August 23rd 2022 (almost 2 years)

Dr. George Church discusses revolutionary technologies in the field of genetic engineering.

Posted on June 29th 2022 (almost 2 years)

Dr. Stuart Phillips discusses how exercise and nutrition influence skeletal muscle-protein turnover and muscle maintenance throughout the lifespan.

Posted on April 28th 2022 (about 2 years)

Dr. Dominic D'Agostino discusses how ketones affect exercise performance, reduce inflammation, and improve neurological health.

Posted on April 11th 2022 (about 2 years)

Dr. Morgan Levine discusses epigenetics and the application of epigenetic aging clocks in quantifying human aging.

Posted on March 9th 2022 (over 2 years)

Dr. Peter Diamandis and Tony Robbins discuss the application of precision medicine and health technologies in slowing human aging.

Posted on February 8th 2022 (over 2 years)

Dr. Eran Elinav discusses the complex interactions between humans and their resident gut microbiomes.

Posted on December 7th 2021 (over 2 years)

Dr. Bill Harris discusses the roles that omega-3 fatty acids play in cardiovascular and neurocognitive health.

Posted on November 2nd 2021 (over 2 years)

Dr. Ashley Mason discusses the practice of cognitive behavioral therapy and sauna use in treating depression.

Posted on October 6th 2021 (over 2 years)

Dr. Mark Mattson discusses how stress is essential to human survival and how exercise and intermittent fasting induce stress to promote health.

Posted on September 27th 2021 (over 2 years)

Dr. Rhonda Patrick and MedCram founders Dr. Roger Seheult and physician assistant Kyle Allred discuss COVID-19 vaccines.

Posted on June 15th 2021 (about 3 years)

Dr. Satchidananda Panda discusses circadian rhythms, the day-night cycles that drive the multifaceted activities of the human body.

Posted on May 24th 2021 (about 3 years)

Dr. Michael Snyder discusses personalized medicine and the use of technologies that monitor metabolism and other health markers.

Posted on February 3rd 2021 (over 3 years)

Dr. Roger Seheult discusses the roles of vaccines, vitamin D, and heat therapy in the prevention of COVID-19.

Posted on December 18th 2020 (over 3 years)

Dr. Steve Horvath discusses epigenetic aging clocks and their use in predicting biological aging and healthspan.

Posted on November 16th 2020 (over 3 years)

A special two-hour Q&A with Dr. Jed Fahey, an expert on sulforaphane, chemoprotection, and phytochemicals.

Posted on October 13th 2020 (over 3 years)

Dr. Giselle Petzinger discusses new findings in Parkinson's disease research, emphasizing exercise's role in delaying disease progression.

Posted on November 6th 2019 (over 4 years)

Dr. David Sinclair discusses the mechanisms that drive human aging and the importance of identifying ways to slow or reverse aging's effects.

Posted on June 10th 2019 (about 5 years)

Dr. Elissa Epel discusses the mechanisms of healthy aging and the associations between stress, telomere length, addiction, eating, and metabolic health.

Posted on February 28th 2019 (over 5 years)

Dr. Matthew Walker discusses the role of sleep in immunity, creativity, and aging.

Posted on January 17th 2019 (over 5 years)

This episode features a Q&A session on fasting-related topics with Dr. Rhonda Patrick and Mike Maser of Zero Fasting Tracker.

Posted on October 1st 2018 (over 5 years)

Dr. Dale Bredesen discusses treatments that may reverse symptoms of mild cognitive decline and Alzheimer’s disease.

Posted on July 9th 2018 (almost 6 years)

Dr. Valter Longo discusses fasting as a means to treat or prevent age-related diseases such as cancer, Alzheimer’s disease, and others.

Posted on March 19th 2018 (about 6 years)

Dr. Charles Raison discusses the role inflammation plays in the development of depression in response to illness and stress.

Posted on December 13th 2017 (over 6 years)

Dr. Eric M. Verdin discusses the roles of the ketogenic diet, beta-hydroxybutyrate, HDAC inhibitors, NAD+, and more in the context of aging.

Posted on October 30th 2017 (over 6 years)

Dr. Satchin Panda discusses the practical aspects of implementing fasting, time-restricted eating, shift work strategies, and more.

Posted on July 31st 2017 (almost 7 years)

Dr. Guido Kroemer discusses immunology, cancer biology, calorie-restriction mimetics, aging, and autophagy.

Posted on June 15th 2017 (about 7 years)

Dr. Jari Laukkanen discusses the role of heat stress in the prevention of cardiovascular & Alzheimer’s disease.

Posted on April 28th 2017 (about 7 years)

Dr. Judith Campisi discusses the role of cellular senescence in the aging process and the development of cancer.

Posted on April 7th 2017 (about 7 years)

Dr. Gordon Lithgow discusses the roles of protein aggregation, iron overload, and others in the aging process.

Posted on January 19th 2017 (over 7 years)

Dr. Jed W. Fahey discusses the health benefits of isothiocyanates, including sulforaphane and moringa.

Posted on January 19th 2017 (over 7 years)

Dr. Roland Griffiths discusses the effects of the psychedelic compound psilocybin on the human brain.

Posted on October 4th 2016 (over 7 years)

Dr. Valter Longo discusses the role of fasting and the fasting-mimicking diet in longevity, cancer & multiple sclerosis.

Posted on July 8th 2016 (almost 8 years)

Dr. Ruth Patterson discusses the role of fasting in the prevention and survivorship of breast cancer.

Posted on July 1st 2016 (almost 8 years)

Dr. Satchin Panda discusses the roles that fasting, time-restricted eating, and circadian rhythms play in human health.

Posted on May 4th 2016 (about 8 years)

Ray Cronise discusses the roles that cold stress, intermittent fasting, and weight loss play in human healthspan.

Posted on April 10th 2016 (about 8 years)

Dr. Dominic D'Agostino discusses the health benefits associated with a modified Atkins diet, ketosis, and supplemental ketones.

Posted on March 14th 2016 (over 8 years)

Dr. Peter Attia discusses dietary strategies to promote longevity and optimal performance.

Posted on January 24th 2016 (over 8 years)

Rich Roll shares his thoughts on self-transformation, the environmental impact of food, and the benefits of eating a plant-based diet.

Posted on January 3rd 2016 (over 8 years)

Dr. Darya Rose & husband Kevin Rose discuss the benefits of meditation, seasonal eating, and more.

Posted on January 3rd 2016 (over 8 years)

Dr. Pierre Capel discusses cold stress, Wim Hof, genetic modification, and cancer immunotherapy.

Posted on January 3rd 2016 (over 8 years)

Wim Hof discusses his unique breathing technique and how it helps him withstand cold stress.

Posted on January 3rd 2016 (over 8 years)

Dr. Ronald Krauss discusses the role that LDL cholesterol plays in heart disease, dyslipidemia, and atherosclerosis.

Posted on August 13th 2015 (almost 9 years)

Dr. Aubrey de Grey discusses technologies that can repair the various types of damage that occur during the aging process.

Posted on July 21st 2015 (almost 9 years)

Tim Ferriss discusses ketosis, the gut microbiome, and monitoring biomarkers to promote performance.

Posted on July 4th 2015 (almost 9 years)

Dr. Bruce Ames discusses the CHORI Bar, a micronutrient- and fiber-dense nutrition bar developed in the Ames laboratory to manage obesity.

Posted on July 4th 2015 (almost 9 years)

Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX.

Posted on February 12th 2015 (over 9 years)

Dr. Bruce Ames discusses his triage theory.

Posted on December 17th 2014 (over 9 years)

Dr. Frans Kuypers discusses his technique to retrieve pluripotent stem cells from placental tissue.

Posted on December 3rd 2014 (over 9 years)

Dr. George Brooks discusses the metabolic pathway known as the “lactate shuttle" and its role in the recovery from traumatic brain injury.

Posted on July 22nd 2014 (almost 10 years)

Dr. Terry Wahls discusses the nutrition protocol she used to reverse her secondary-progressive multiple sclerosis.