In this Aliquot, Dr. Andrew Huberman and I explore the complexities of digital engagement, share strategies for managing...
Dr. Darren Candow and Dr. Rhonda Patrick discuss the science of creatine for muscle performance and brain health.
In this Aliquot, I explore how genetics, lifestyle, and potassium balance influence sodium's role in...
Dr. Rhonda Patrick discusses saturated fats and LDL, luteolin's benefits, glyphosate risks, natural vs. artificial flavors, and black cumin seed effects.
In this Aliquot, you'll hear expert insights from Drs. Bruce Ames, Andrew Huberman, Axel Montagne, and me...
Dr. Kerry Courneya and Dr. Rhonda Patrick discuss the remarkable science behind exercise oncology.
In this Aliquot, I briefly describe the science and concerns surrounding microplastics and identify ways to lessen...
Dr. Rhonda Patrick's testimony before the United States Senate Special Committee on Aging.
Dr. Rhonda Patrick discusses microdosing nicotine, GlyNac benefits, intermittent fasting and hair loss, and cold & flu relief.
In this Aliquot, Drs. Matt Walker, Satchin Panda, and Andrew Huberman explore how to harness the benefits of natural light...
Dr. Rhonda Patrick and Brady Holmer discuss training principles from their comprehensive guide.
In this Aliquot, we explore strategies for optimizing muscle mass through exercise, nutrition, and supplements with...
Dr. Rhonda Patrick discusses GLP-1 agonists, alpha-lipoic acid, ubiquinone vs. ubiquinol, calcium needs, and liquid biopsy cancer screening.
In Aliquot #107, we heard from ten experts who shared how they put their knowledge into practice—applying insights from their own research and...
Recovery is essential to any fitness routine, allowing the body to heal, rebuild, and grow stronger after workouts. But it involves more than...
Lactate often gets a bad rap due to its close association with lactic acid. But lactate plays a distinctly different and often-underappreciated role...
Dr. Rhonda Patrick discusses _Akkermansia muciniphila_, vitamin B1's effect on blood sugar, emulsifiers in food, and electrolyte supplements.
Testosterone is a steroid hormone produced primarily in the testes in males and in smaller amounts in the ovaries in females. It's crucial...
Dr. Rhonda Patrick dives into the science of protein and discusses intake requirements, its ties to longevity, and debunks several protein-related myths.
Dr. Rhonda Patrick discusses silicone safety, grounding, pentadecanoic acid, and the potential benefits of olive leaf extract and peptides.
Mitochondrial health and overall health are intrinsically linked. Identifying ways to boost mitochondrial biogenesis...
Mitochondria are best known for their energy-producing roles, but they also help regulate cellular metabolism, signaling, and apoptosis...
Dr. Rhonda Patrick discusses her supplement stack, avoiding microplastics, creatine for brain health, and mRNA vaccine autoimmunity risks.
Aerobic exercise and resistance training are essential for optimal health. However, finding the time to do both can be challenging...
Dr. Rhonda Patrick explains how HIIT, circadian-timed eating, and quality sleep improve metabolic health and reduce chronic disease risk.
Dr. Rhonda Patrick discusses if smoked salmon is carcinogenic, high-dose melatonin, creatine on workout vs. non-workout days, and the Neurocode brain scan.
Microplastics are ubiquitous in everyday life. This episode details how they impact our health and ways that we can limit our exposure.
Dr. Rhonda Patrick discusses xylitol safety, strategies to reduce hemoglobin A1C, klotho and dementia risk, and the timing of hormone replacement therapy.
Dr. Layne Norton and I discuss fat loss, resistance training, seed oils, the carnivore diet, artificial sweeteners, and much more.
As we age, our hair changes: It often turns gray and becomes finer, and it might even fall out—permanently...
Dr. Luc van Loon discusses optimal protein intake & distribution strategies for stimulating muscle protein synthesis.
Processed foods fall on a spectrum, from minimally processed (like oatmeal or canned tomatoes) to ultra-processed...
In this episode, we’re taking a deep dive into alcohol. We’ll explore the science, misconceptions, controversies, and health effects of this widely used drug.
Foods contain a vast array of nutrients, fiber, and bioactive compounds packaged up into a complex physical-chemical structure called...
Apolipoprotein B, or ApoB for short, is a structural protein found in LDL particles. If ApoB gets oxidized or modified, it can drive the formation...
Dr. Rhonda Patrick discusses fish oil and Afib risk, hyperbaric oxygen therapy, supplements for kids, and curcumin's impact on testosterone.
Dr. Andrew Huberman discusses the role of dopamine in driving motivation and offers practical tools for enhancing mood and focus.
Dr. Rhonda Patrick discusses resistant starch, red light therapy risks, stem cells, and the link between benzodiazepines and dementia in her latest Q&A session.
Dr. Levine details his research findings that show how a structured exercise regimen can reverse up to 20 years of heart aging.
Living long, healthy lives isn't just about luck; it's about putting in the effort and staying committed. There's plenty of scientific evidence out there tha...
I've interviewed many scientists over the years, each with their own expertise and specialty, ranging from exercise science and kinesiology to gene editing a...
Vitamins are substances that our bodies need to develop and function normally. When considering vitamins, we tend to think of the usual suspects – A, C, D, E...
Dr. Rhonda Patrick explores collagen peptides, high-dose niacin and vitamin B6, avoiding nano- and microplastics in her latest Q&A.
Roughly half of adults in the US have hypertension, commonly known as high blood pressure. Defined as having a systolic pressure of 130 or higher or a diasto...
This is my keynote presentation from the 2024 CrossFit Health Summit where I explored how vigorous exercise and heat stress contribute to longevity.
Adequate, quality sleep is essential for the body's recovery and repair, promoting optimal physical and mental health. Getting a good night's sleep can be ch...
Dr. Rhonda Patrick explores blood tests to track health, statin alternatives, mitochondrial supplements, and vitamin B12 and autism risk in her latest Q&A.
In this solo episode, I'm taking an in-depth look at magnesium – a critical yet frequently underestimated mineral in our health.
In part I of this two-part series on the future of aging research, we discussed the hallmarks of aging and the cutting-edge therapies aimed at understanding ...
In my keynote at LongevityFest 2023, I share powerful habits to delay aging and improve healthspan, presented at the American Academy of Anti-Aging Medicine.
Dr. Rhonda Patrick explores creatine, dairy's effect on polyphenols, eggs' health impact, and new weight loss drugs like Ozempic in her latest Q&A.
Researchers in the field of aging science have identified nine hallmarks of aging – observable biological patterns of dysfunction that occur as an organism a...
Muscle disuse atrophy, or muscle wasting, poses serious risks, particularly for older adults, promoting irreversible muscle loss, frailty, and disease. Rebui...
Dr. Rhonda Patrick explores iodine supplementation, choline & TMAO, curcumin safety, and red yeast rice in her latest Q&A.
From preconception to toddlerhood and early childhood, there's a lot to consider when deciding to have a baby. Dr. Rhonda Patrick spent many months researchi...
Dr. Peter Attia presents practical steps we can implement to improve our health, emphasizing the importance of each aspect while providing actionable advice.
Dr. Rhonda Patrick explores melatonin's antioxidant properties, curcumin supplementation, antinutrients, and SARMs in her latest Q&A.
Time-restricted eating involves consuming meals within a specific daily time window. However, choosing the optimal time frame for that window is influenced b...
This episode, featuring Dr. Rhonda Patrick, dives deep into the science and practicality of incorporating vigorous-intensity exercise into our lives.
Time-restricted eating involves consuming meals within a specific daily time window but is distinct from true fasting, which involves extended food abstinenc...
Dr. Rhonda Patrick explores cheese's health impact, ergothioneine's longevity properties, sleep and joint supplements, and red light therapy in her latest Q&A.
Hormesis is a compensatory defense response to a stressor that conditions the body against future stressors. Cold exposure, a powerful hormetic stressor, act...
Dr. Rhonda Patrick describes strategies you can apply immediately to enhance your health and prevent chronic disease.
Hormesis is a compensatory defense response to a stressor that conditions the body against future stressors. Heat exposure – from sauna use, hot tubs, or eve...
Dr. Rhonda Patrick explores supplemental tyrosine, lion's mane, cordyceps, aging tests, and sunscreen's efficacy and safety in a Q&A.
As research progresses, my dietary and supplement habits adapt. At times, it's the ineffable quality of consciousness, submerged in a mental calculus of cost...
Dr. Martin Gibala discusses HIIT's health benefits and describes common HIIT protocols.
Dr. Rhonda Patrick discusses concerns about early smartphone and tablet access among kids and its effects on mental health later in life.
Dr. Rhonda Patrick explores growth hormone secretagogues, spermidine's longevity role, methylene blue, whey protein, and solutions for scar tissue in a Q&A.
Sulforaphane, a bioactive compound derived from broccoli, broccoli sprouts, and red kale, exerts potent antioxidant and anti-inflammatory properties that can...
Dr. Rhonda Patrick explores taurine's longevity role, cocoa flavanols, training adaptations, and oral hyaluronic acid in a Q&A.
Berberine is a plant-derived compound that may be beneficial for treating a wide range of chronic health conditions associated with obesity, such as hyperten...
Having a healthy body composition, with plenty of lean mass – in the form of muscle and bones – is essential for health throughout the lifespan. Achieving a ...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Chris McGlory discusses muscle protein dynamics, emphasizing how omega-3 helps maintain muscle mass in older adults.
The blood-brain barrier is a collection of membranes that separate the central nervous system from the circulatory system. It permits the passage of nutrient...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
It's tempting to think of dementia as something in the long-distant future – a condition that only affects older people. But the factors that drive dementia ...
Heat therapy (saunas, exercise, hot baths) can enhance slow-wave sleep. This video explores exercise and heat's joint role in sleep regulation.
Vascular dysfunction, the loss of normal endothelial tone and permeability of blood vessels, is a common feature of most forms of dementia, including Alzheim...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
A ketogenic diet is high in fat, moderate in protein, and low in carbohydrates. Research shows that it mimics fasting by inducing metabolic switching – the c...
Advanced glycation end-products, or AGEs for short, are created when the sugars, amino acids, and fats in food encounter heat. AGEs also form in the body dur...
Photobiomodulation (PBM) involves using light therapy, such as red light, laser, or infrared therapy, to stimulate, heal, regenerate, and protect the body. F...
Your skin is a crucial barrier to the outside world – the first line of defense against environmental exposures, and the primary means by which the body reta...
Chronic inflammation plays a key role in the development of many chronic diseases, including cancer, cardiovascular disease, and diabetes. When it comes to m...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Bone density is crucial throughout the lifespan, but it takes on even greater importance as we age, as bone mass really begins to decline. Resistance trainin...
APOE is a protein involved in lipid transport. A variant of APOE called APOE4 is the primary genetic risk factor for Alzheimer's disease. APOE4 also increase...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Axel Montagne discusses blood-brain barrier dysfunction in dementia and early-stage age-related cognitive decline.
Apolipoprotein B, or ApoB for short, is a protein involved in lipid metabolism and is a robust predictor of cardiovascular disease risk. Healthy lifestyle be...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Protein is an essential component of a healthy eating pattern because it supports the growth, development, and maintenance of skeletal muscle. While animal-d...
Although people experience muscle soreness to varying degrees, soreness is perfectly normal after training and typically occurs following exposure to novel s...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Incorporating resistance training into your exercise regimen presents a scheduling dilemma – there's simply not enough time. Performing time-efficient workou...
Migraine is a neurological disorder that typically manifests as an intense, debilitating headache and is often accompanied by nausea, vomiting, and light sen...
Meditation, in its various forms, has powerful effects on the brain and body. In this second part of our two-part series on meditation, we'll discuss some of...
Meditation is a form of mental training geared toward improving aspects of a person's core neurocognitive function, such as the regulation of attention and e...
Dr. Brad Schoenfeld studies the importance of resistance exercise in maintaining muscle mass.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Protein is essential for building and maintaining muscles. Aiming for about 1.2 to 1.6 grams of protein per kilogram of body weight (about 0.5 to 0.7 grams p...
Consuming sufficient protein is essential for muscle growth and maintenance. Emphasis on specific amino acids within protein, particularly the branched-chain...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Exercise stresses the entire body – the heart, lungs, bones, muscles, and even the brain. The body responds by inducing a wide range of adaptations that incr...
When people exercise as part of a treatment for alcohol abuse disorder it reduces their volume of alcohol consumption. But why? One reason may be FGF21.
Protein is an essential component of a healthy eating pattern because it supports the growth, development, and maintenance of skeletal muscle tissue. Having ...
The progressive loss of skeletal muscle mass and strength that occurs with aging, referred to as sarcopenia, begins as early as our 30s or 40s. Many factors ...
High-intensity interval training, or HIIT for short, is a popular form of exercise involving short bursts of intense aerobic exercise interspersed with perio...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Exposure to environmental toxins – in the food we eat, the water we drink, and the air we breathe – is largely unavoidable. But monitoring our exposures and ...
Choline is an essential nutrient that plays important roles in human health. It provides methyl groups for many aspects of metabolism, is a component of cell...
Sugar substitutes are food products or additives that provide the sweet taste of sugar, without the calories. Evidence suggests that sugar substitutes have s...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Non-steroidal anti-inflammatory drugs, or NSAIDs, are among the most widely used drugs worldwide, available in both prescription and over-the-counter forms, ...
Dr. George Church discusses revolutionary technologies in the field of genetic engineering.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Chocolate and its principal component, cocoa, are popular topics – no doubt because they taste so good. But a wide range of beneficial health effects have be...
Continuous glucose monitors – CGMs, for short – are wearable devices that measure blood glucose levels through a tiny sensor placed under the skin. The CGM c...
Vitamin K is a type of fat-soluble vitamin that participates in blood clotting, cardiovascular health, and bone metabolism. Naturally occurring forms of vita...
Lifestyle factors and new technologies offer the promise of living longer, healthier lives, but is there a limit to the human lifespan? This episode explores the different theories supporting this hotly debated topic.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dietary fiber is a broad term that refers to the non-digestible components of fruits and vegetables. Gut microbes break down certain types of fiber, releasin...
Dr. Stuart Phillips discusses how exercise and nutrition influence skeletal muscle-protein turnover and muscle maintenance throughout the lifespan.
Meat – especially red meat – is perhaps one of the most polarizing topics in the nutrition world today. Some camps tout the benefits of eating an all-meat di...
While some research suggests drinking alcohol improves health, an abundance of evidence indicates that drinking alcohol also harms health. Particularly, high...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Patrick's keynote: compromised intestinal barrier affects human health—cardiometabolic function, neurological health, behavior, and more.
The Mediterranean diet pattern is rich in micronutrient-dense foods such as vegetables, fish, and olive oil and has been shown to reduce the risk of cardiova...
Aging – a process that began the moment we were born – is generally thought of as inevitable. But could aging become reversible in the future? Technologies l...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Dominic D'Agostino discusses how ketones affect exercise performance, reduce inflammation, and improve neurological health.
The idea of aging "gracefully" – looking, feeling, and thinking well as the years pass – is not only appealing, but (science suggests) also achievable. Exerc...
Multiple sclerosis (MS) is an autoimmune neurodegenerative disorder that destroys myelin, the insulating layer that surrounds neurons. The causes of MS are c...
MedCram co-founder Kyle Allred discusses sauna's exercise mimetic, anti-inflammatory, mood-elevating, and detoxifying properties in this episode.
Dr. Morgan Levine discusses epigenetics and the application of epigenetic aging clocks in quantifying human aging.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
In response to cold-water immersion, the body increases circulation of norepinephrine. This physiological response sets off a cascade of adaptive effects that affect metabolism, the brain, and genetic expression.
Autoimmune diseases such as type 1 diabetes, rheumatoid arthritis, and multiple sclerosis occur when the immune system mistakes the body's own proteins for t...
A healthy intestinal barrier limits the transport of pathogens and endotoxins from the gut to the bloodstream; however, increased gut permeability (known as ...
Dr. Peter Diamandis and Tony Robbins discuss the application of precision medicine and health technologies in slowing human aging.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
The cardioprotective effects of omega-3s are pretty well established. But the research on omega-3s has also revealed that they're involved in nearly every as...
Dr. Eran Elinav discusses the complex interactions between humans and their resident gut microbiomes.
Early studies of omega-3 fatty acid intake demonstrated dramatic biological effects. Since then, the body of research enumerating the profound anti-inflammat...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Small changes can make big differences in how long and how well we live. Diet stands out as low-hanging fruit for influencing our lifespan. Optimizing macron...
The arrival of a new year is a great opportunity to make health-focused resolutions – promises to ourselves that we're going to live better, healthier, and (...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Many people suffer from insomnia, which is often driven by change, especially change that affects relationships, employment, or family dynamics. Cognitive be...
Circadian rhythms play key roles in metabolic health and ultimately influence body weight, performance, and susceptibility to diseases like diabetes and canc...
This episode discusses qualities of the psychedelic experience that most lend psilocybin to be potentially therapeutically beneficial for depression.
Overeating – whether it's an occasional practice or a chronic problem – can promote weight gain and a host of other health problems such as type 2 diabetes a...
While infection with the SARS-CoV-2 virus shares symptoms with the common cold and influenza such as sore throat, cough, and runny nose, there are critical d...
Dr. Bill Harris discusses the roles that omega-3 fatty acids play in cardiovascular and neurocognitive health.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
This episode has the answers to hot topic questions about the COVID-19 vaccines, such as: Is the spike protein made from the vaccines dangerous? Will the vac...
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Protein is essential for maintaining muscle mass as we age. Modulating protein intake via dietary intake or fasting can have variable effects on aging and mu...
Dr. Ashley Mason discusses the practice of cognitive behavioral therapy and sauna use in treating depression.
The classic ketogenic diet is high in fat and low in protein and carbohydrates. The ease of following a ketogenic diet varies from person to person, dependin...
Regulating the amount of light in our environment is crucial for a good night's sleep and a good mood the next day. Habits such as using blue light-emitting ...
When a person consumes a ketogenic diet, profound metabolic changes occur as the body shifts from burning glucose to using fatty acids and ketones. These cha...
Eating a typical Western diet – high in processed foods and sugar-sweetened beverages – raises blood glucose and insulin levels, promotes inflammation, and c...
Zinc is an essential nutrient that participates in many biological processes and plays critical roles in immune function, protein synthesis, wound healing, D...
In recent decades, lifestyle practices have emerged as viable strategies for treating symptoms of depression. Online resources that combine healthful practic...
Inflammation is an important aspect of immunity. Robust evidence indicates that increased inflammation is linked with depression. Some scientists think that ...
The physiological responses to sauna use are incredibly similar to those experienced during moderate- to vigorous-intensity exercise. As a result, sauna use ...
Diet plays an essential role in immune function. Consequently, deficiencies or insufficiencies in vitamins or minerals can impair immune function. The gut mi...
Statins can reduce the risk of heart disease by 30 to 40 percent due to their ability to increase LDL receptor activity and reduce blood cholesterol levels. ...
Vitamin D is a hormone produced in the body. People who have poor vitamin D status are more likely to test positive for COVID-19. In the setting of COVID-19,...
Airplanes are closed, cramped spaces that seem ideal for COVID-19 transmission. Even so, surprisingly few COVID-19 infections have been reported from air tra...
Cholesterol is vital to human health, but an oversimplified view of cholesterol — that high-density lipoprotein (HDL) cholesterol is good, and low-density li...
Having a healthy, robust immune system is crucial for our survival. Critical players in the body's antiviral immune response are interferons. Certain lifesty...
Sleep affects aspects of our mental and cognitive health. Not getting enough sleep triggers the onset of a "loneliness phenotype," driving people who are sle...
Poor sleep reduces the body's insulin sensitivity and changes a person's appetite, increasing the preference for high carbohydrate foods like pizza, pasta, a...
Traditional vaccines take many years to develop. A recent innovation in vaccine technology involves exploitation of messenger RNA, or mRNA, to facilitate rap...
Coffee consumption is associated with protection from several chronic diseases. Coffee's beneficial effects may stem from its ability to induce autophagy; ho...
Keeping our brains sharp throughout the lifespan is essential for optimal performance. Lifestyle behaviors such as exercise, dietary modification, and sauna ...
Recent discoveries in the field of epigenetics suggest we might be able to slow aging, based on the realization that not everyone ages at the same rate. Evid...
This is a special mashup episode, featuring a collection of clips on a range of topics related to supplements — including Rhonda’s evolving supplement routin...
Parkinson's disease is a progressive neurodegenerative disorder with no cure. It typically manifests later in life and is caused by the destruction of neuron...
Although many beneficial effects of time- or calorie-restricted eating in humans have been identified, many questions still remain regarding fitness and perf...
Circadian rhythms modulate a wide array of the body's physiological processes, ultimately influencing body weight, performance, and susceptibility to disease...
Autophagy, a type of cellular recycling program, influences many aspects of health and disease, including cancer, neurodegenerative disease, and aging. Nutri...
Chronic stress impacts our mental and physical health. Stress increases levels of hormones like adrenaline and cortisol, which in turn, can increase a person...
Sulforaphane exerts beneficial – and somewhat unconventional – effects in humans to promote health. For example, sulforaphane promotes the urinary excretion ...
“If you can not measure it, you can not improve it.” - William Thompson Getting regular checkups and undergoing blood tests are fundamental to maintaining...
Dr. Mark Mattson discusses how stress is essential to human survival and how exercise and intermittent fasting induce stress to promote health.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Rhonda Patrick and MedCram founders Dr. Roger Seheult and physician assistant Kyle Allred discuss COVID-19 vaccines.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Compared to people with the lowest blood concentrations of EPA and DHA (combined), those with the highest blood concentrations were as much as 17 percent less likely to die from all causes of premature death.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Eating too much or too little generally has obvious effects on our health. But a growing body of evidence suggests that when we eat matters, too. Late-night ...
Mounting evidence demonstrates that various forms of fasting may be beneficial as a complementary treatment against cancer. Fasting makes cancer cells more v...
Dr. Satchidananda Panda discusses circadian rhythms, the day-night cycles that drive the multifaceted activities of the human body.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Sulforaphane, an isothiocyanate compound derived from broccoli sprouts and certain cruciferous vegetables, exerts a wide range of beneficial effects in human...
The conversion of glucoraphanin to sulforaphane in broccoli sprouts requires myrosinase, an enzyme co-located within the leaves, stems, and other components ...
Sulforaphane switches on mechanisms that protect against cancer and other environmental insults. Sulforaphane is produced when the plants' cells are damaged ...
Sulforaphane, an isothiocyanate compound, is the most potent naturally occurring inducer of the body's key detoxification enzymes. While sulforaphane is deri...
Insulin-like growth factor-1, or IGF-1 for short, is a protein that plays critical roles in major growth pathways in the human body. It influences nearly eve...
Time-restricted eating, which involves taking in food within a small window of time during the day and fasting for the remainder, can improve certain biomark...
Various ancient practices, including meditation, hot yoga, and sauna, may aid in the treatment of depression. Whether the medical community will embrace thes...
Roughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for...
People who have depression often have elevated biomarkers of inflammation. These markers can chronically activate the body's inflammatory response system, pr...
This episode of the aliquot features a collection of clips covering a range of topics related to fasting - both intermittent and prolonged. Specific topics ...
This collection of clips covers some of the many health benefits associated with the use of traditional Finnish saunas and other forms of whole-body hyperthe...
In this first episode of the Aliquot podcast, Rhonda discusses topics such as her pre-pregnancy diet, exercise, and sleep; which supplements she included and...
Dr. Michael Snyder discusses personalized medicine and the use of technologies that monitor metabolism and other health markers.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
In this short video, Dr. Rhonda Patrick describes one of the mechanisms that drives the beneficial effects of sleep on the brain.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Roger Seheult discusses the roles of vaccines, vitamin D, and heat therapy in the prevention of COVID-19.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Steve Horvath discusses epigenetic aging clocks and their use in predicting biological aging and healthspan.
Dr. Steve Horvath found a way to measure biological aging – a type of "clock" – based on the methylation pattern of an organism's genome. This video primer explains the basics of epigenetic clocks, the topic of our interview with Dr. Steve Horvath.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Broccoli sprouts contain more glucoraphanin, the precursor to sulforaphane, than mature broccoli. Glucoraphanin activates the Nrf2 pathway to protect cells from oxidative stress and damage. In this episode, we describe the basics of sprouting broccoli seeds.
A special two-hour Q&A with Dr. Jed Fahey, an expert on sulforaphane, chemoprotection, and phytochemicals.
Dr. Giselle Petzinger discusses new findings in Parkinson's disease research, emphasizing exercise's role in delaying disease progression.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Comprehensive overview: Breast milk's nutritional and non-nutritional components, and health benefits for mother and infant through breastfeeding
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
COVID-19 Q&A Part 2: Rhonda Patrick, Ph.D. answers subscriber questions in a multi-part series.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Rhonda Patrick makes her ninth appearance on the Joe Rogan Experience.
Dr. Patrick covers vitamin C's diverse aspects: bioavailability, immune function, viral protection, lung health, cancer impact, exercise effects, and more!
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
COVID-19 Q&A Series Part 1: Rhonda Patrick, Ph.D. addresses subscriber questions in this multi-part series.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Rhonda explains NAD+: importance for aging, decline with age, boosters (nicotinamide riboside, nicotinamide mononucleotide), and data in animals and humans.
Dr. Rhonda Patrick on Kevin Rose Show: metformin, magnesium L-threonate, fish oil, brain health, sulforaphane, goitrogenic activity, sauna, and more.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Resveratrol's science, effects in animals and humans, mechanisms, supplementation, and safety.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. David Sinclair discusses the mechanisms that drive human aging and the importance of identifying ways to slow or reverse aging's effects.
Sauna use boosts lifespan and overall health supported by compelling data from observational, interventional, and mechanistic studies.
Dr. Patrick discusses some of the compelling evidence that suggests exercise is a tool for preventing or managing the symptoms of depression.
Dr. Elissa Epel discusses the mechanisms of healthy aging and the associations between stress, telomere length, addiction, eating, and metabolic health.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
The production of melatonin begins to increase 2-3 hours before our normative bedtime, which may be a signal to the pancreas to begin suppressing the production of insulin.
Several studies have established causation showing that sleep duration is a major determinant of insulin sensitivity.
Dr. Matthew Walker discusses the role of sleep in immunity, creativity, and aging.
This episode features a Q&A session on fasting-related topics with Dr. Rhonda Patrick and Mike Maser of Zero Fasting Tracker.
Dr. Rhonda Patrick makes her eighth appearance on the Joe Rogan Experience.
Dr. Dale Bredesen discusses treatments that may reverse symptoms of mild cognitive decline and Alzheimer’s disease.
This short recipe video shows a fun, tasty way to eat salmon roe. Salmon roe is rich in the omega-3 fatty acid, docosahexaenoic acid, in its phospholipid form.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Valter Longo discusses fasting as a means to treat or prevent age-related diseases such as cancer, Alzheimer’s disease, and others.
Dr. Charles Raison discusses the role inflammation plays in the development of depression in response to illness and stress.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Rhonda Patrick makes her seventh appearance on the Joe Rogan Experience.
Dr. Eric M. Verdin discusses the roles of the ketogenic diet, beta-hydroxybutyrate, HDAC inhibitors, NAD+, and more in the context of aging.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Several associative studies that have found a link between saturated fat and heart disease... should we be concerned?
This is a video on how to plausibly increase the sulforaphane created from the glucoraphanin in your broccoli sprouts by up to 3.5-fold.
Our genes influence the way we absorb and metabolize micronutrients. Nutrigenomics looks at the influence genetic variation has over micronutrient absorption/metabolism and the biological consequences of this dynamic relationship.
In this video Dr. Rhonda Patrick shares her recipe for low-carb lemon tart and demonstrates how to make it.
Dan Pardi: Ph.D. candidate studying sleep neurobiology at Stanford and University of Leiden, co-founder of Dan’s Plan online wellness company.
Dr. Rhonda Patrick talks about transgenerational effects of caloric restriction on longevity, B-vitamins silencing bad genes, cognitive stimulation reversing neurodegenerative disease, exercise increases neurogenesis, and ways in which vitamin D might influence aging.
Dr. Satchin Panda discusses the practical aspects of implementing fasting, time-restricted eating, shift work strategies, and more.
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Dr. Guido Kroemer discusses immunology, cancer biology, calorie-restriction mimetics, aging, and autophagy.
Dr. Jari Laukkanen discusses the role of heat stress in the prevention of cardiovascular & Alzheimer’s disease.
Dr. Judith Campisi discusses the role of cellular senescence in the aging process and the development of cancer.
Dr. Gordon Lithgow discusses the roles of protein aggregation, iron overload, and others in the aging process.
Science on refined sugar: mortality, aging, brain function, memory, neuroinflammation, cancer, sex hormones, addiction & more.
Systemic inflammation is an important mechanism that research shows may have a very interesting relationship with depression.
Dr. Jed W. Fahey discusses the health benefits of isothiocyanates, including sulforaphane and moringa.
Dr. Roland Griffiths discusses the effects of the psychedelic compound psilocybin on the human brain.
Dr. Rhonda Patrick makes her fifth appearance on the Joe Rogan Experience.
This podcast is about one of the most important biological pathways you could possibly take the time to learn about: the NRF2 pathway.
Dr. Valter Longo discusses the role of fasting and the fasting-mimicking diet in longevity, cancer & multiple sclerosis.
Dr. Ruth Patterson discusses the role of fasting in the prevention and survivorship of breast cancer.
Dr. Satchin Panda discusses the roles that fasting, time-restricted eating, and circadian rhythms play in human health.
A modest change on the "micronutrient smoothie" that also talks about the beneficial compounds that don't qualify as micronutrients.
Ray Cronise discusses the roles that cold stress, intermittent fasting, and weight loss play in human healthspan.
Dr. Dominic D'Agostino discusses the health benefits associated with a modified Atkins diet, ketosis, and supplemental ketones.
Dr. Peter Attia discusses dietary strategies to promote longevity and optimal performance.
Dr. Rhonda Patrick explains cold shock as hormesis, a beneficial stressor that triggers adaptive processes, promoting resilience.
Rich Roll shares his thoughts on self-transformation, the environmental impact of food, and the benefits of eating a plant-based diet.
Dr. Darya Rose & husband Kevin Rose discuss the benefits of meditation, seasonal eating, and more.
Dr. Pierre Capel discusses cold stress, Wim Hof, genetic modification, and cancer immunotherapy.
Wim Hof discusses his unique breathing technique and how it helps him withstand cold stress.
Dr. Patrick's keynote lecture at MBOG Congres 2015 in the Netherlands covers micronutrient inadequacy and Dr. Bruce Ames' triage theory.
This episode is a presentation Dr. Rhonda Patrick delivered at the Biohacker Summit in Helsinki, Finland in 2016.
Drs. Erica and Justin Sonnenburg both research the interaction between diet and the trillions of bacteria in the gut.
Dr. Ronald Krauss discusses the role that LDL cholesterol plays in heart disease, dyslipidemia, and atherosclerosis.
Rhonda explains chronic stress's impact on brain, gut, immune system, and aging. Meditation buffers and improves cognitive and biological aging.
Dr. Aubrey de Grey discusses technologies that can repair the various types of damage that occur during the aging process.
Tim Ferriss discusses ketosis, the gut microbiome, and monitoring biomarkers to promote performance.
Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX.
In this video, Dr. Rhonda Patrick summarizes a recent study that found that frequency of sauna use was associated with increased decreased risk of death. Using the sauna 2-3 times per week was associated with 24% lower all-cause mortality and 4-7 times per week decreased all-cause mortality by 40%.
This video breaks down, point-by-point what gene polymorphisms you might look at, and how they relate to very specific micronutrients.
Is cancer just bad luck? To some degree, yes... but there's also a very, very large environmental and lifestyle component.
Dr. Bruce Ames discusses his triage theory.
Dr. Frans Kuypers discusses his technique to retrieve pluripotent stem cells from placental tissue.
Dr. George Brooks discusses the metabolic pathway known as the “lactate shuttle" and its role in the recovery from traumatic brain injury.
Dr. Rhonda Patrick makes her third appearance on the Joe Rogan Experience.
There may be something special about sources of omega-3 that are richer in the phosphatidylcholine form of DHA.
Dr. Rhonda Patrick explains what antioxidants are, why they are important, and how they prevent DNA damage, a well-known cancer initiator.
Dr. Terry Wahls discusses the nutrition protocol she used to reverse her secondary-progressive multiple sclerosis.
Dr. Rhonda Patrick is on The Tim Ferriss Show in episode #12 entitled "Rhonda Patrick on Life Extension, Performance, and More".
Decreased consumption of chlorophyll containing vegetables, decreased absorption, and increased excretion is largely the primary reasons why apprximately 45% of US population is deficient in magnesium.
Dr. Patrick describes how magnesium, an essential mineral that ~56% of the US population is deficient in, can help you maximize your mitochondria to increase oxidative capacity and, potentially, enhance exercise performance.
Dr. Rhonda Patrick makes her second appearance on the Joe Rogan Experience.
Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentially even muscle mass.
Dr. Rhonda Patrick makes her first appearance on the Joe Rogan Experience.
In this podcast, we discuss and critically analyze a recent headline-grabbing editorial that was published in the Annals of Internal Medicine that reviewed three studies on the topic of multivitamins and chronic disease prevention. We analyze the important shortcomings of the studies and talk about the mechanism.