Related Episodes for Ketone supplementation as a possible treatment for neurodegenerative diseases | Dominic D'Agostino

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

“The main ingredient-interaction evidence concerns polyphenol oxidase. A small controlled crossover study found that a high-PPO banana smoothie greatly reduced circulating flavan-3-ol metabolites compared with a low-PPO berry drink or capsule control.”

“Diamandis and Robbins are a dynamic duo, having paired up with co-author Dr. Robert Hariri to write Life Force, a best-selling book that describes breakthroughs in precision medicine and health technologies that can help people live longer, healthier, more fulfilling lives – in the very near future.”

“Not only is salmon roe a good source of DHA, it also provides protein, vitamins, minerals, and astaxanthin – an antioxidant compound that gives salmon its reddish or pinkish tint. In human studies, astaxanthin reduces biomarkers of oxidative stress.”

“Ultimately, we all have to weigh the merits and the trade-offs of portable devices for ourselves and our children individually, but it might mean holding out on the tablet until they're a little older, setting rules around it, and certainly demonstrating our own self-discipline in their use.”

“Exercise promotes the release of insulin-like growth factor-1 and its downstream targets, growth hormone and brain-derived neurotrophic factor, to drive muscle and neuron growth. Sauna use increases these factors, too, and when used post-exercise, may have a synergistic effect to improve cardiovascular, musculoskeletal, and neurological health.”

“Although scientists have identified other lifestyle behaviors that can help prevent the build-up of amyloid plaques by boosting the capacity for glymphatic clearance – such as exercise and adequate intake of omega-3 – the most important factor by far is a good night's sleep, especially deep sleep.”

“There is so much to say when we talk about the NRF2 pathway and isothiocyanates like sulforaphane that we had to pack it into 47 minutes and break it into a few key sections. Key sections: For a more in-depth breakdown click the timeline link at the top of this page!”

“Human trials suggest that alpha-lipoic acid can modestly improve selected lipid measures. A dose-response meta-analysis of 12 studies found reductions in total cholesterol, LDL cholesterol, and triglycerides across doses from 300 to 1,200 milligrams per day.”

“A meta-analysis in older adults found greater gains in lean mass and strength when creatine accompanied training, while a systematic review found the most consistent benefits after at least 12 weeks of combined use. Dr. Phillips also highlights emerging cognitive evidence.”