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Related Episodes for Rhonda Patrick and Tim Ferriss discuss metformin as a possible cancer prevention drug

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Why 'choosing the stairs' reduces early death (VILPA study) | Dr. Martin Gibala

Sep 28, 2023

“Preliminary findings from a study analyzing UK Biobank data with over 25,000 participants suggest that even 3-4 minutes of VILPA daily could reduce all-cause mortality risk by 25-30%.”

exercise aging mortality
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COVID-19 "Long Haulers" — Psychosis and heart inflammation | Roger Seheult

Mar 9, 2021

“A perplexing aspect of SARS-CoV-2, the novel coronavirus that causes COVID-19, is that people respond to it in disparate ways — some exhibiting no symptoms at all, and others experiencing life-threatening complications.”

covid-19 inflammation vaccine
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How Elevated Blood Sugar Affects the Brain and Heart

Apr 4, 2025

“Her practical message is to reduce the frequency and size of large glucose exposures. Foods with intact fiber, protein, and minimally processed carbohydrates digest more slowly than refined added sugar, while regular exercise gives skeletal muscle a large destination for circulating glucose.”

sugar brain aging inflammation
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Environmental and genetic causes of Parkinson's disease | Giselle Petzinger

Oct 27, 2020

“While some forms of Parkinson's disease are genetic, most cases involve a complex interaction between genetic and environmental risk factors. In the early 1980s, intravenous drug users inadvertently injected a contaminated drug and developed parkinsonian symptoms overnight.”

parkinson's metabolism inflammation genetics
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165
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Epigenetic Aging: How old is your DNA?

Dec 11, 2020

“Sure, those dates on the calendar pass at the same rate for everybody, but some people appear to age slower (or faster) than others – with vastly different age-related physical changes and disease risks.”

epigenetics aging biomarkers genetic engineering
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Evidence-Based Treatments for Pattern Hair Loss

Sep 24, 2025

“A smaller comparative study found improved hair density, shaft size, and anagen-follicle proportion with 2 percent ketoconazole shampoo, while its authors called for larger controlled studies. These results support individualized combinations rather than one universal protocol.”

hormones inflammation drug rhonda
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Exercise and Nutrition Strategies That Support Bone Density After 65

Mar 13, 2026

“In a two-year trial of 237 postmenopausal women, approximately 9 to 10 grams per day combined with resistance training and walking did not add a bone-density benefit, so its role is better framed around muscle and physical function.”

menopause vitamin d exercise aging
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How Vigorous Exercise and Lactate Support Brain Health

Jun 23, 2025

“Controlled human studies support acute brain-related responses to high-intensity exercise. Six short all-out cycling intervals improved selected learning and executive measures while increasing circulating BDNF, IGF-1, and VEGF; lactate tracked several of these changes.”

exercise brain aging mitochondria
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Eating to extend healthspan: overnutrition vs undernutrition | Ray Cronise

Feb 28, 2020

“Studies of centenarians suggest that lower levels of inflammation are associated with longevity. Different types of fiber provide fuel to diverse species of bacteria in the gut, which then synthesize byproducts that regulate the inflammatory process.”

diet aging inflammation fasting
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170
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Gordon Lithgow, Ph.D. on Protein Aggregation, Iron Overload & the Search for Longevity Compounds

Apr 7, 2017

“How too much iron can lead to protein aggregation and how vitamin D can prevent it. A program, directed by Gordon, called the Caenorhabditis Intervention Testing Program which tests potential longevity compounds that may extend the lifespan of several different species of worms.”

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